AZD9668 Relative Bioavailability
NCT01034982 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2010-02-05
Summary
The study is designed to investigate the pharmacokinetic behaviour of the free base formulation of AZD9668. The study will compared the relative bioavailability of the free base formulation at two different dose levels compared to the tosylate salt formulation.
Conditions
Interventions
- DRUG
-
AZD9668
20 mg
- DRUG
-
AZD9668
60 mg
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Emma Harrop · AstraZeneca R&D
-
Rainard Fuhr · Parexel
Study Design
- Allocation
- RANDOMIZED
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-11-30
- Primary Completion
- 2009-12-31
- Completion
- 2009-12-31
Countries
- Germany
Study Locations
More Related Trials
-
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled AZD4604 in Healthy Japanese and Chinese Participants.
NCT06519968 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I, Exploratory, Single Centre, Single Oral Dose AZD9668 and Intravenous Microdose of [C14] AZD9668, Healthy Subject
NCT01161355 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, and Pharmacokinetics of AZD7268 After Single Ascending Oral Doses in Healthy Subjects
NCT00796965 ·Status: COMPLETED ·Phase: PHASE1
-
This Study Will Investigate How Food and Age Effect the Way the Body Handles the AZD5069 Drug Given as a Oral Dose
NCT01083238 ·Status: COMPLETED ·Phase: PHASE1
-
A Study in Healthy Subjects to Investigate Pharmacokinetics of AZD5423 When Administered in Different Ways
NCT01635985 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Doses of AZD8566.
NCT00749333 ·Status: COMPLETED ·Phase: PHASE1
-
To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of Inhaled AZD8683
NCT01419600 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison of Two Formulations of AZD5363 and the Effect of Food on Pharmacokinetic Exposure, Safety and Tolerability
NCT01895946 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics of AZD7295 Capsules
NCT01097408 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers
NCT06951880 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
A Study in Healthy Subjects to Investigate Pharmacokinetics of AZD8683 When Administered in Different Ways
NCT01666613 ·Status: WITHDRAWN ·Phase: PHASE1
-
Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of AZD8566.
NCT00844103 ·Status: COMPLETED ·Phase: PHASE1
-
To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ascending Doses of Inhaled AZD7594
NCT01636024 ·Status: COMPLETED ·Phase: PHASE1
-
Blood Levels and Effects of GSK1325756 in Healthy Adult Volunteers Aged 40 to 80 Years Old
NCT01267006 ·Status: COMPLETED ·Phase: PHASE1
-
Relative Bioavailability of Phase II and Phase III Formulations of AZD0530
NCT00771979 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess the Safety, Tolerability, and Pharmacokinetics (Movement of Drugs Within the Body) of AZD2693 in Healthy Participants
NCT05107336 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Relative Bioavailability and Safety of Different Formulations of AZD4831 in Fasted State in Healthy Volunteers.
NCT05457270 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Safety, Tolerability and Activity of AZD5069 When Given as a Single Dose to Healthy Male and/or Female Subjects
NCT00953888 ·Status: COMPLETED ·Phase: PHASE1
-
Investigate the Safety Tolerability and Pharmacokinetics of Multiple Doses of AZD1236
NCT00767052 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I, Safety Tolerability and Pharmacokinetics of AZD4831 to Treat Cardiovascular Disease
NCT03136991 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1 Study to Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants.
NCT05329623 ·Status: COMPLETED ·Phase: PHASE1
-
AZD 2066 Single Dose Formulation and Food Effect Study in Healthy Volunteers
NCT00690404 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Compare Two Different Tablet Formulations of AZD8931 in Healthy Males and Females
NCT01330758 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO5545965 in Healthy Volunteers
NCT01864226 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate Safety, Tolerability and Pharmacokinetics With Single and Multiple Ascending Doses of AZD1446
NCT00902993 ·Status: COMPLETED ·Phase: PHASE1