Observational Study of the Effects Intravenous Bortezomib Has on Osteoblast (Cell That is Responsible for Bone Formation) Activity in Multiple Myeloma Patients.
NCT01026701 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 104
Last updated 2014-04-28
Summary
The purpose of this study is to measure the markers related to bone metabolism before and after the use of bortezomib injection in patients with multiple myeloma and to evaluate the effect bortezomib injection has on bone disease.
Conditions
Interventions
- DRUG
-
injection into a vein 1.3 mg/m2 twice a week for 21 days
Sponsors & Collaborators
-
Janssen Korea, Ltd., Korea
lead INDUSTRY
Principal Investigators
-
Janssen Korea, Ltd. Clinical Trial · Janssen Korea, Ltd.
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-03-31
- Primary Completion
- 2009-11-30
- Completion
- 2009-11-30
More Related Trials
-
An Efficacy and Safety Study of Bortezomib in Participants Previously Treated for Multiple Myeloma With Limited Kidney Function
NCT00718640 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Bortezomib as Consolidation Therapy in Patients With Multiple Myeloma
NCT00416273 ·Status: COMPLETED ·Phase: PHASE3
-
Observational Study to Evaluate the Efficacy and Safety of Bortezomib, Melphalan, Prednisone (VMP) in Participants With Multiple Myeloma
NCT02474563 ·Status: COMPLETED
-
A Japan Phase I/II Study of Bortezomib in Relapsed or Refractory Multiple Myeloma Patients
NCT00752518 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Post-Approval Pharmacokinetic Study of Bortezomib in Participants With Multiple Myeloma
NCT01801436 ·Status: COMPLETED ·Phase: PHASE3
-
An Observational Study of Chinese Multiple Myeloma Patients Treated With Velcade
NCT01675245 ·Status: COMPLETED
-
Effect of Low Dose Bortezomib on Bone Formation in Smoldering Myeloma Patients
NCT00983346 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Subcutaneous Versus Intravenous Administration of Bortezomib in Patients With Multiple Myeloma in China
NCT01812096 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Consolidation Therapy With Bortezomib in Elderly Patients With Multiple Myeloma
NCT00416208 ·Status: COMPLETED ·Phase: PHASE3
-
The Efficacy of Velcade on Bone Tissue During Myelomatosis (Bone Marrow Cancer)
NCT00436059 ·Status: COMPLETED ·Phase: PHASE2
-
Bone Effect of Bortezomib in Patients With Relapsed/Refractory Multiple Myeloma
NCT01062230 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Risk Factors and Genetic Association With Bortezomib-induced Peripheral Neuropathy in Multiple Myeloma
NCT03210753 ·Status: UNKNOWN
-
Bortezomib Based Consolidation in Multiple Myeloma Patients Completing Stem Cell Transplant
NCT01706666 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Assessing Safety and Effectiveness of BORTEZOMIB Combination Therapy (Bortezomib + Doxorubicin Hydrochloride + Dexamethasone) in Previously Untreated Multiple Myeloma Patients
NCT00561743 ·Status: COMPLETED ·Phase: PHASE2
-
Bortezomib-Melphalan Conditioning Regimen vs Melphalan for Frontline Transplant Eligible Patients With Multiple Myeloma
NCT02197221 ·Status: COMPLETED ·Phase: PHASE3
-
Velcade Consolidation Bone Study
NCT01286077 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate Optimized Retreatment and Prolonged Therapy With Bortezomib
NCT01910987 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Bortezomib-containing Regimens in Newly Diagnosed Patients With t (4; 14) Positive Multiple Myeloma
NCT00570180 ·Status: COMPLETED ·Phase: PHASE2
-
Expanded Access Protocol (EAP) to Provide Bortezomib to Patients With Multiple Myeloma Who Have Received at Least 2 Previous Lines of Therapy and Are Refractory to or Have Relapsed After Their Last Therapy for Multiple Myeloma
NCT00440635 ·Status: COMPLETED
-
An Efficacy and Safety Study of Bortezomib Re-treatment in Multiple Myeloma
NCT00431769 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma
NCT05257083 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Pharmacokinetic Study of Bortezomib in Taiwanese Participants With Multiple Myeloma
NCT02268890 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluating the Efficacy and Safety of the Lower Dose of Bortezomib Plus Busulfan and Melphalan as a Conditioning Regimen in Patients With Multiple Myeloma Undergoing Autologous Peripheral Blood Stem Cell Transplantation- KMM103 Study
NCT01255527 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Bortezomib in Treating Patients With Multiple Myeloma Who Have Undergone an Autologous Peripheral Blood Stem Cell Transplant
NCT00288028 ·Status: COMPLETED ·Phase: PHASE1
-
Modified Bortezomib-based Combination Therapy for Multiple Myeloma
NCT02559154 ·Status: UNKNOWN ·Phase: PHASE4