Magnetic Resonance Imaging (MRI) in Predicting Response to Sunitinib Malate in Patients With Locally Advanced or Metastatic Kidney Cancer
NCT01026337 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 43
Last updated 2019-06-25
Summary
Rationale: Diagnostic procedures, such as MRI, may help doctors predict a patient's response to treatment and help plan the best treatment.
Purpose: This clinical trial is studying MRI in predicting response to sunitinib malate in patients with locally advanced or metastatic kidney cancer.
Conditions
- Renal Cell Carcinoma
- Stage III Renal Cell Cancer
- Stage IV Renal Cell Cancer
Interventions
- GENETIC
-
mutation analysis
Correlative study
- OTHER
-
pharmacological study
Correlative study
- PROCEDURE
-
dynamic contrast-enhanced magnetic resonance imaging
Undergo DCE-MRI
- DRUG
-
sunitinib malate
Given orally
- OTHER
-
immunohistochemistry staining method
Correlative study
- OTHER
-
laboratory biomarker analysis
Correlative study
Sponsors & Collaborators
-
Abramson Cancer Center at Penn Medicine
lead OTHER
Principal Investigators
-
Stephen Keefe · Abramson Cancer Center at Penn Medicine
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-04-30
- Primary Completion
- 2015-12-31
- Completion
- 2018-11-30
Countries
- United States
Study Locations
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