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Trichomoniasis: Genotype and Phenotype Correlations in African American Women

NCT00998530 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 231

Last updated 2019-05-23

No results posted yet for this study

Summary

The hypothesis to be tested in this trial is that the different epidemiologic (including racial differences) and phenotypic manifestations exhibited by Trichomonas clinical isolates during infection are correlated with their genotypic strain classification. Two specific aims are proposed to test that hypothesis. Specific aim 1. Assess the significance of genotypic or phenotypic differences in the Trichomonas strains among African American women by HIV status. Specific aim 2. Determine the significance of genotypic or phenotypic differences in the Trichomonas strains circulating among women from two different racial groups, African American women and Caucasian women. The overall goals of these specific aims are to identify racial differences in the genotypic and phenotypic characteristics of Trichomonas strains, and to develop the ability to identify and classify Trichomonas infections in order to prioritize treatment and epidemiologic follow-up of individuals infected with isolates associated with adverse clinical outcomes (HIV transmission or acquisition, pregnancy complications, virulence, or drug resistance).

Conditions

  • Trichomonas Infections

Sponsors & Collaborators

  • Mississippi State Department of Health

    collaborator OTHER_GOV

  • University of Mississippi Medical Center

    lead OTHER

Principal Investigators

  • John C Meade, PhD · University of Mississippi Medical Center

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-09-30
Primary Completion
2019-05-31
Completion
2019-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00998530 on ClinicalTrials.gov