CYP19 Genetic Polymorphism & Aromatase Inhibitor(AI)
NCT00973505 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2009-09-09
Summary
The purpose of this study is to investigate the relationship between the side effects(especially arthralgia and arthritis) which appear in the patients who are prescribed aromatase inhibitor(AI) and the CYP19 genetic polymorphisms.
Conditions
- Breast Neoplasms
- Arthralgia
- Arthritis
- Genetic Polymorphism
Interventions
- DRUG
-
Aromatase Inhibitor(Femara or Arimidex)
Femara(Letrozole) 2.5mg 1tab qd, Arimidex(Anastrozole) 1mg 1tab qd
Sponsors & Collaborators
-
Korea University
collaborator OTHER -
Korea University Anam Hospital
lead OTHER
Principal Investigators
-
Eun Sook Lee, MD, PhD · Korea University Anam Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-03-31
- Primary Completion
- 2010-09-30
- Completion
- 2010-09-30
Countries
- South Korea
Study Locations
More Related Trials
-
Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace)
NCT01908556 ·Status: UNKNOWN ·Phase: PHASE4
-
Study of Cytochrome P450 Polymorphisms (CYP2D6, CYP3A4/5 and CYP2C19) in Breast Cancer Patients
NCT01169792 ·Status: COMPLETED
-
Targeted Physiotherapeutic Treatment for Aromatase Inhibitor-associated Musculoskeletal Pain in Breast Cancer Survivors
NCT04560699 ·Status: COMPLETED ·Phase: NA
-
Rheumatological Evaluation of Anastrozole and Letrozole as Adjuvant Treatment in Post-menopausal Women With Breast Cancer
NCT00688909 ·Status: COMPLETED ·Phase: PHASE4
-
A Cohort Study of Musculoskeletal Health in Patients With Breast Cancer During Aromatase Inhibitors Therapy
NCT05921617 ·Status: UNKNOWN
-
Measuring Musculoskeletal Symptoms in Patients Receiving Aromatase Inhibitors
NCT01074320 ·Status: COMPLETED
-
Changes in Knee Articular Cartilage Volume in Women on Aromatase Inhibitors
NCT00111241 ·Status: COMPLETED
-
Exemestane + Celecoxib vs Exemestane + Placebo in Metastatic Breast Cancer
NCT00525096 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Rheumatologic Tolerability of Letrozole in Postmenopausal Patients With Hormone Receptor Positive Breast Cancer
NCT00329940 ·Status: COMPLETED ·Phase: PHASE3
-
Prospective Study of UDP-gluconoryltransferase 2B17 Genotype as a Predictive Marker of Exemestane PK and PD
NCT01655004 ·Status: UNKNOWN ·Phase: NA
-
Impact of Obesity on the Efficacy of Endocrine Therapy With Aromatase Inhibitors
NCT01758146 ·Status: UNKNOWN ·Phase: PHASE3
-
Joint Pain and Medication Adherence in Postmenopausal Women Receiving Aromatase Inhibitors
NCT00954564 ·Status: COMPLETED
-
Impact of a Food Supplement on Musculoskeletal Pain in Women With Breast Cancer Treated With Aromatase Inhibitors.
NCT07199556 ·Status: COMPLETED ·Phase: NA
-
Breast Density Change Predicting Response to Adjuvant Aromatase Inhibitor
NCT01765049 ·Status: ACTIVE_NOT_RECRUITING
-
CYP2D6 Genotype on the Clinical Effect of Tamoxifen
NCT00973037 ·Status: UNKNOWN
-
Yoga for Aromatase Inhibitor-associated Joint Pain
NCT01951976 ·Status: COMPLETED ·Phase: NA
-
A Cohort Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms
NCT02874222 ·Status: COMPLETED
-
Comparative Evaluation of Efficacy and Safety of Toremifene, Tamoxifen, and Aromatase Inhibitor Plus Ovarian Function Suppression in Hormone Receptor-Positive Early Breast Cancer Among Non-Low-Risk Premenopausal Women: A Real-World Study
NCT05801705 ·Status: UNKNOWN
-
Aromatase Inhibitor Clinical Trial
NCT00228956 ·Status: UNKNOWN
-
Glucosamine and Chondroitin for Aromatase Inhibitor Induced Joint Symptoms in Women With Breast Cancer
NCT00691678 ·Status: COMPLETED ·Phase: PHASE2
-
Arthralgia During Anastrozole Therapy for Breast Cancer
NCT00323479 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of the Association Between CYP2D6 Genetic Polymorphisms and the Treatment Effect of Tamoxifen
NCT00532454 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)
NCT01824836 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Hormones and Physical Exercise (HOPE) Study
NCT02056067 ·Status: COMPLETED ·Phase: NA
-
Geriatric Oncology Assessment and Coping Skills Training for Older Women on Aromatase Inhibitor Therapy
NCT07232056 ·Status: NOT_YET_RECRUITING ·Phase: NA