Development of a Valid Test Battery for Assessing Driving Ability When Influenced by Drugs.

Summary

The purpose of the validation study is to develop a valid test battery for assessing driving ability in a driving simulator when influenced by drugs. Ethanol has known, well-documented and well-characterized effects on driving behaviour and accident risk, and will be used to assess the simulator test scenarios' sensitivity to drug effects. Once the test scenarios have been refined and their ability to predict driving accident risk have been validated, we plan to use the simulator to assess driving ability under the influence of different drugs suspected to produce driving impairment.

Conditions

• Automobile Driving

Interventions

DRUG

ethanol

BAC level 0.5 g/dL (drink + placebo pill). Drink with 2,4 grams per kilo body weight, administered orally during 60 min, administration ending 30 min prior to start of testing. Placebo pill.

DRUG

Ethanol

BAC level 1.0 g/dL (drink + placebo pill). Drink with 3,6 grams per kilo body weight, administered orally during 60 min, administration ending 30 min prior to start of testing. Placebo pill.

OTHER

Placebo drink

Placebo drink containing no alcohol + placebo pill

Sponsors & Collaborators

• SINTEF Health Research

  collaborator OTHER

• Norwegian University of Science and Technology

  collaborator OTHER

• Norwegian Institute of Public Health

  collaborator OTHER_GOV

• St. Olavs Hospital

  lead OTHER

Principal Investigators

• Lars Slørdal, PhD, MD · Norwegian University of Science and Technology

• Gunnar D Jenssen · SINTEF Health Research

Study Design

Allocation

NON_RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

25 Years

Max Age

50 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2009-09-30

Primary Completion

2009-11-30

Completion

2010-11-30

Countries

• Norway

Study Locations