Study of Blood Samples From High-Risk Postmenopausal Women Who Received Treatment on Breast Cancer Prevention Clinical Trials NSABP-P-1 or NSABP-P-2
NCT00967239 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1881
Last updated 2015-05-08
Summary
RATIONALE: Studying the genes expressed in samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research study is looking at blood samples from high-risk postmenopausal women who received treatment on breast cancer prevention clinical trials NSABP-P-1 or NSABP-P-2.
Conditions
Interventions
- GENETIC
-
DNA analysis
- GENETIC
-
polymorphism analysis
- OTHER
-
laboratory biomarker analysis
- OTHER
-
pharmacogenomic studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
NSABP Foundation Inc
lead NETWORK
Principal Investigators
-
James N. Ingle, MD · Mayo Clinic
Eligibility
- Min Age
- 35 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-04-30
- Primary Completion
- 2015-12-31
More Related Trials
-
The Clinical and Economic Impact of Pharmacogenomic Testing for Tamoxifen Metabolism in Postmenopausal Women Receiving Tamoxifen for Prevention of Recurrent Breast Cancer
NCT00830973 ·Status: COMPLETED
-
Arzoxifene or Tamoxifen in Preventing Breast Cancer in Premenopausal Women at High Risk for Breast Cancer
NCT00253539 ·Status: COMPLETED ·Phase: PHASE2
-
Adaptation to Living With a BRCA1/2 Mutation
NCT01866865 ·Status: COMPLETED
-
Changes in Breast Density and Blood Hormone Levels in Postmenopausal Women Receiving Anastrozole or Exemestane for Breast Cancer
NCT00516698 ·Status: COMPLETED
-
Tamoxifen in Preventing Breast Cancer in Women at Increased Risk for Breast Cancer
NCT00096369 ·Status: TERMINATED ·Phase: PHASE2
-
Letrozole in Preventing Breast Cancer in Healthy Postmenopausal Women at High Risk for Breast Cancer
NCT01077453 ·Status: COMPLETED ·Phase: PHASE1
-
Genetic Counseling for Menopausal Therapy Decision-Making for Women at Increased Risk for Breast Cancer
NCT00349011 ·Status: COMPLETED ·Phase: NA
-
Tamoxifen Pharmacogenetics and Clinical Effects
NCT00228930 ·Status: COMPLETED
-
Celecoxib in Preventing Breast Cancer in At-Risk Premenopausal Women
NCT00056082 ·Status: COMPLETED ·Phase: PHASE2
-
Gene Expression Profiling to Help Define the Need for Neo-Adjuvant Chemotherapy in HR+, HER- Breast Cancer Patients
NCT05666258 ·Status: RECRUITING
-
Protocol for Women at Increased Risk of Developing Breast Cancer
NCT00291135 ·Status: COMPLETED ·Phase: PHASE2
-
Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion
NCT06033092 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease
NCT00080756 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Pharmacogenetics as a Predictor of Toxicity in Pre-Menopausal Women Receiving Doxorubicin and Cyclophosphamide in Early Breast Cancer
NCT00352872 ·Status: TERMINATED
-
Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors
NCT01196936 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Hormone Therapy in Treating Postmenopausal Women With Receptor-Positive Breast Cancer
NCT00002646 ·Status: COMPLETED ·Phase: PHASE3
-
Genetic Counseling in Women at Risk for BRCA1 or BRCA2 Mutations
NCT00416754 ·Status: COMPLETED ·Phase: NA
-
The Effects of Short-term Preoperative Treatment With Hormonal Therapy on Gene Profiles in Breast Cancer
NCT04129216 ·Status: COMPLETED ·Phase: PHASE2
-
Tamoxifen Citrate Decision Aids for Women at Increased Risk of Breast Cancer
NCT00967824 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Bexarotene in Preventing Breast Cancer in Women at Genetic Risk
NCT00055991 ·Status: COMPLETED ·Phase: PHASE1
-
Letrozole in Preventing Breast Cancer in Postmenopausal Women Who Are at Increased Risk for Breast Cancer Due to High Breast Density
NCT00238316 ·Status: COMPLETED ·Phase: PHASE2
-
Cluster Randomized Trial Comparing Interventions to Enhance Genetic Counseling Among Breast Cancer Patients
NCT01789684 ·Status: COMPLETED ·Phase: NA
-
Effect of Pharmacogenomics Differences in Phase I and II Metabolism of Tamoxifen on Efficacy and Toxicity
NCT00886535 ·Status: COMPLETED
-
Evaluation of the Association Between CYP2D6 Genetic Polymorphisms and the Treatment Effect of Tamoxifen
NCT00532454 ·Status: TERMINATED ·Phase: PHASE2
-
Letrozole in Preventing Breast Cancer in Postmenopausal Women
NCT00090857 ·Status: COMPLETED ·Phase: PHASE2