Study to Evaluate the Effect of Bimosiamose on Ozone Induced Sputum Neutrophilia
NCT00962481 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 18
Last updated 2010-01-06
Summary
The purpose of this study is to evaluate the safety, tolerability and efficacy of repeated inhalative doses of Bimosiamose on ozone induced sputum neutrophilia in healthy subjects.
Conditions
- Chronic Obstructive Pulmonary Disease (COPD)
Interventions
- DRUG
-
Bimosiamose
- DRUG
Sponsors & Collaborators
-
Revotar Biopharmaceuticals AG
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
Countries
- Germany
Study Locations
More Related Trials
-
Study of Biomarkers of Airway Inflammation (0000-128)
NCT00869596 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacological Effect of Lysozyme for Chronic Obstructive Pulmonary Disease and Asthma With Sputum Symptom
NCT01715493 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
NCT07201051 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Trial to Evaluate the Efficacy and Safety of Faropenem Medoxomil In the Treatment of Chronic Bronchitis
NCT00255983 ·Status: TERMINATED ·Phase: PHASE3
-
Effect of Ensifentrine on Sputum Markers of Inflammation in COPD
NCT05270525 ·Status: RECRUITING ·Phase: PHASE2
-
Phase 2a, 28-day Investigational Use Study of ARINA-1 in Non-Cystic Fibrosis Bronchiectasis (NCFBE) With Excess Mucus and Cough
NCT05495243 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization
NCT07088926 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Expectorant Activity of Oral N-acetylcystein (NAC) in Patients With Stable Chronic Bronchitis
NCT00205647 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Test Whether Different Doses of BI 1291583 Help People With Bronchiectasis
NCT05238675 ·Status: COMPLETED ·Phase: PHASE2
-
A Study in Patients With Non-cystic Fibrosis Bronchiectasis to Test How Well Different Doses of BI 1323495 Are Tolerated and How BI 1323495 Affects Biomarkers of Inflammation
NCT04656275 ·Status: TERMINATED ·Phase: PHASE1
-
Tobramycin in Bronchiectasis Colonized With Pseudmonas Aeruginosa
NCT03715322 ·Status: UNKNOWN ·Phase: PHASE3
-
PH-797804 LPS Study in Healthy Volunteers
NCT02084485 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis
NCT00769119 ·Status: COMPLETED ·Phase: PHASE2
-
Study of the Effects of High-dose N-acetylcysteine (NAC) in Idiopathic Pulmonary Fibrosis (IPF)
NCT00639496 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluate the Efficacy and Safety of N02RS1 in Patient With Acute Bronchitis
NCT02637310 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis
NCT05415137 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Safety and Efficacy of Oral BAY85-8501 in Patients With Non-CF (Cystic Fibrosis) Bronchiectasis
NCT01818544 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability, and Clinical Activity of ASM-024 Administered to Patients With GOLD 2 or GOLD 3 Chronic Obstructive Pulmonary Disease (COPD)
NCT01855230 ·Status: COMPLETED ·Phase: PHASE2
-
Assessment of INS1007 in Participants With Non-Cystic Fibrosis Bronchiectasis
NCT03218917 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Assess the Effects of Dexpramipexole in Participants With Eosinophilic COPD
NCT06533553 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Efficacy and Safety of Mepolizumab as an Add-on Treatment in Chronic Obstructive Pulmonary Disease (COPD)
NCT02105961 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects
NCT02058407 ·Status: TERMINATED ·Phase: PHASE1
-
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis
NCT04631016 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
NCT06559150 ·Status: RECRUITING ·Phase: PHASE2
-
A Study Measuring the Effectiveness, Safety, and Tolerability of BMS-986278 in Participants With Lung Fibrosis
NCT04308681 ·Status: COMPLETED ·Phase: PHASE2