Effect of Sitagliptin in Impaired Glucose Tolerance
NCT00961363 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2010-03-22
Summary
The purpose of this study is to examine the safety and efficacy of sitagliptin 100 mg every day (q.d.) in improving hyperglycemia and endothelial dysfunction in subjects with impaired glucose tolerance.
Conditions
- Impaired Glucose Tolerance
Interventions
- DRUG
-
Sitagliptin
sitagliptin 100 mg per day
- DRUG
-
Placebo
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Lee-Ming Chuang, MD, PhD · Department of Internal Medicine, National Taiwan University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-12-31
- Primary Completion
- 2011-06-30
Countries
- Taiwan
Study Locations
More Related Trials
-
Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)
NCT00541775 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Assess the Efficacy and Safety of Sitagliptin in Recently Diagnosed, Naive Type 2 Diabetics With Inadequate Glycemic Control on Diet and Exercise (0431-158)
NCT00832390 ·Status: COMPLETED ·Phase: PHASE4
-
Sitagliptin Comparative Study in Patients With Type 2 Diabetes (0431-049)
NCT00449930 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Different Doses of Sitagliptin (MK-0431) in Participants With Type 2 Diabetes Mellitus (MK-0431-014)
NCT00481663 ·Status: COMPLETED ·Phase: PHASE2
-
Sitagliptin and Glucagon Counterregulation
NCT02256189 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Test the Safety and Efficacy of Adding Sitagliptin in Patients With Type 2 Diabetes Mellitus (MK0431-074)
NCT00813995 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Chiglitazar Compare With Sitagliptin in Type 2 Diabetes Patients
NCT02173457 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Trial to Investigate the Pharmacokinetics/Pharmacodynamics of Sitagliptin
NCT00960453 ·Status: COMPLETED ·Phase: PHASE1
-
Study on Exploring the Effect of DPP-4 Inhibitors on β-cell Function by Using the Two-step Hyperglycemic Clamp
NCT02386943 ·Status: UNKNOWN ·Phase: PHASE4
-
Sitagliptin in Prevention of Type 2 Diabetes Mellitus
NCT01038648 ·Status: WITHDRAWN ·Phase: PHASE3
-
An Open-Label, Single- & Multiple-Dose Study to Investigate the Pharmacokinetics of Sitagliptin 100 mg in Healthy Chinese Adult Subjects (0431-108)(COMPLETED)
NCT00642798 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess the Efficacy and Safety of Sitagliptin Added to the Regimen of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (0431-189)
NCT00875394 ·Status: COMPLETED ·Phase: PHASE3
-
Sitagliptin Mechanism of Action Study in Patients With Type 2 Diabetes Mellitus (0431-059)
NCT00704132 ·Status: COMPLETED ·Phase: PHASE1
-
Sitagliptin Versus Insulin Dose Increase in Type 2 Diabetes on Insulin Treatment
NCT01100125 ·Status: COMPLETED ·Phase: PHASE4
-
Treatment With Sitagliptin in Non-obese Japanese Patients With Type 2 Diabetes Mellitus
NCT01642108 ·Status: UNKNOWN ·Phase: NA
-
Use of Sitagliptin for Stress Hyperglycemia or Mild Diabetes Following Cardiac Surgery
NCT01970462 ·Status: TERMINATED ·Phase: PHASE4
-
Contribution of Pancreatic αcells Function to Blood Glucose Regulation in Chinese Type 2 Diabetics- the Effect of Sitagliptin on Glucagon Secretion, Insulin Secretion and Insulin Resistance in Chinese Type 2 Diabetics
NCT01610154 ·Status: COMPLETED ·Phase: PHASE4
-
Sitagliptin vs. Pioglitazone as add-on Treatments in Patients With Type 2 Diabetes Uncontrolled on the Full-dose Metformin Plus Sulfonylurea
NCT03125694 ·Status: COMPLETED ·Phase: PHASE3
-
Glucose Variability With DPP-4 Inhibition
NCT01751321 ·Status: UNKNOWN ·Phase: NA
-
The Effect of Sitagliptin in Type 2 Diabetes Mellitus With Inadequate Glycemic Control (MK0431-118)
NCT00832624 ·Status: TERMINATED ·Phase: PHASE4
-
Effects of Sitaglpitin on Endothelial Function During the OGTT in T2DM
NCT02301806 ·Status: UNKNOWN ·Phase: PHASE4
-
Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea
NCT01195090 ·Status: COMPLETED ·Phase: PHASE4
-
Sitagliptin Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus
NCT00337610 ·Status: COMPLETED ·Phase: PHASE3
-
Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM
NCT00820573 ·Status: COMPLETED ·Phase: PHASE4
-
Predictive Parameters for Efficacy of Sitagliptin and Metformin Combination
NCT00969566 ·Status: COMPLETED ·Phase: PHASE4