Dose-escalation Study of CX-3543 in Patients With Advanced Solid Tumors or Lymphomas
NCT00955786 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2009-08-10
Summary
This phase 1 study of CX-3543 is designed to test the safety, tolerability and highest safe dose level of this drug in patients with advanced solid tumor cancers.
Conditions
Interventions
- DRUG
-
CX-3543
Escalating doses of CX-3543 administered intravenously daily for 5 consecutive days every 21 days.
Sponsors & Collaborators
-
Cylene Pharmaceuticals
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-07-31
- Primary Completion
- 2007-07-31
- Completion
- 2008-12-31
Countries
- United States
Study Locations
More Related Trials
-
Phase I and Pharmacology Study of Camptothecin-20-O-Propionate Hydrate (CZ48) in Patients With Solid Tumors or Lymphoma
NCT00947739 ·Status: COMPLETED ·Phase: PHASE1
-
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC)
NCT03897036 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma
NCT01177397 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study to Evaluate the Safety, Tolerability of DN1508052-01 in Advanced Solid Tumors
NCT03934359 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety and Pharmacokinetics of CDX-0158 in Adult Patients With Advanced Solid Tumors
NCT02642016 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.
NCT01353625 ·Status: COMPLETED ·Phase: PHASE1
-
Study of CC-122 to Evaluate the Safety, Tolerability, and Effectiveness for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myeloma
NCT01421524 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Efficacy of Cisplatin Micelle Injection (HA132) in Patients With Advanced Malignant Solid Tumors
NCT05478785 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors
NCT05142592 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Open-Label Study to Assess the Safety/Tolerability in Patients With Solid Tumors
NCT00820560 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Study OF CDC-501 in Patients With Solid Tumors
NCT00046735 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate Maximum Tolerated Dose of Oral CB-03-10 With Dose Expansion Phase, in Advanced Solid Tumors
NCT03863145 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Study to Evaluate the Safety and Tolerance of SYHX1903 in Patients With Relapsed/Refractory Hematologic Malignancies
NCT05055791 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid Malignancies
NCT02740985 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Solid Tumors or Non Hodgkin's Lymphoma
NCT01356173 ·Status: COMPLETED ·Phase: PHASE1
-
Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers
NCT05691517 ·Status: RECRUITING ·Phase: PHASE1
-
Safety and Efficacy of LCL161 in Patients With Solid Tumors
NCT01098838 ·Status: COMPLETED ·Phase: PHASE1
-
Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies
NCT03422679 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Safety and Pharmacokinetic Study of RRx-001 in Cancer Subjects
NCT01359982 ·Status: COMPLETED ·Phase: PHASE1
-
Phase1 Study of Gemcitabine HCl Oral Formulation(D07001-F4) in Patients With Advanced Solid Malignancies and Malignant Lymphomas
NCT01800630 ·Status: COMPLETED ·Phase: PHASE1
-
Study of XL820 in Adults With Solid Tumors
NCT00129571 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate Fadraciclib (CYC065), in Subjects With Advanced Solid Tumors and Lymphoma
NCT04983810 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of CS5001 in Patients With Advanced Solid Tumors and Lymphomas
NCT05279300 ·Status: RECRUITING ·Phase: PHASE1
-
CLN-418 Study on Subjects With Advanced Solid Tumors
NCT05306444 ·Status: COMPLETED ·Phase: PHASE1
-
A Safety And Pharmacokinetic Study With CVX-045 In Patients With Advanced Solid Tumors
NCT00879554 ·Status: COMPLETED ·Phase: PHASE1