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Effects of Prednisolone and Infliximab on the Regulation of Urea Synthesis in Active Inflammatory Bowel Disease

NCT00955123 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2012-10-12

No results posted yet for this study

Summary

Loss of total mass of muscles (catabolism) is a serious clinical problem in patients with active inflammatory bowel disease (IBD). The investigators have earlier shown that the liver plays an important role in this stress-catabolism by increasing the production of urea during the inflammatory process.

The purpose of this study is to examine the effect of the anti-inflammatory drugs prednisolone and infliximab on the regulation of the urea synthesis in patients with active ulcerative colitis and Crohn's disease.

Conditions

  • Inflammatory Bowel Diseases

Sponsors & Collaborators

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Karen Louise Thomsen, MD · Aarhus University Hospital

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-01-31
Completion
2011-12-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00955123 on ClinicalTrials.gov