Aliskiren for Proteinuric IgAN Despite Angiotensin Blockade
NCT00922311 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2015-07-03
Summary
Study objective: To investigate the potential anti-proteinuric efficacy of aliskiren, a novel direct renin inhibitor (DRI), in addition to angiotensin receptor blocker (ARB) in immunoglobulin A nephropathy (IgAN) patients at risk of developing progressive renal failure.
Conditions
Interventions
- DRUG
-
Aliskiren
Titrate from 150 mg daily to 300 mg daily
Sponsors & Collaborators
-
Queen Mary Hospital, Hong Kong
collaborator OTHER -
United Christian Hospital
collaborator OTHER -
The University of Hong Kong
lead OTHER
Principal Investigators
-
Sydney CW Tang, MD · The University of Hong Kong
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-07-31
- Primary Completion
- 2010-12-31
- Completion
- 2010-12-31
Countries
- China
Study Locations
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