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Resistance to Methotrexate in Patients With Acute Lymphoblastic Leukemia in Relapse or Remission

NCT00899899 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 135

Last updated 2015-09-30

No results posted yet for this study

Summary

RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about cancer and the development of drug resistance in patients.

PURPOSE: This laboratory study is looking at resistance to methotrexate in patients with acute lymphoblastic leukemia in relapse or remission.

Conditions

Interventions

GENETIC

microarray analysis

GENETIC

reverse transcriptase-polymerase chain reaction

OTHER

laboratory biomarker analysis

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Children's Oncology Group

    lead NETWORK

Principal Investigators

  • Richard Gorlick, MD · Children's Hospital at Montefiore

Eligibility

Max Age
120 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1998-06-30
Primary Completion
2005-03-31
Completion
2006-04-30

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00899899 on ClinicalTrials.gov