Tamoxifen Resistance in Women With Stage I, Stage II, Stage IIIA, or Stage IIIB Breast Cancer
NCT00899197 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 2
Last updated 2017-08-01
Summary
RATIONALE: Studying samples of blood from patients with breast cancer in the laboratory may help doctors identify and learn more about biomarkers related to tamoxifen resistance.
PURPOSE: This laboratory study is looking at tamoxifen resistance in women with stage I, stage II, stage IIIA, or stage IIIB breast cancer.
Conditions
Interventions
- DRUG
-
tamoxifen citrate
- GENETIC
-
gene expression analysis
- GENETIC
-
protein expression analysis
- OTHER
-
immunoenzyme technique
- OTHER
-
laboratory biomarker analysis
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Wake Forest University Health Sciences
lead OTHER
Principal Investigators
-
Steven A. Akman, MD · Wake Forest University Health Sciences
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-05-31
- Primary Completion
- 2009-03-31
- Completion
- 2012-06-30
Countries
- United States
Study Locations
More Related Trials
-
Tamoxifen in Treating Women With Breast Cancer
NCT00003678 ·Status: UNKNOWN ·Phase: PHASE3
-
Tamoxifen Compared With LY353381 in Treating Women With Newly Diagnosed Breast Cancer
NCT00005886 ·Status: COMPLETED ·Phase: PHASE1
-
Biological Response to Tamoxifen (TAM) in Patients With Breast Cancer Non Metastatic RH+
NCT01220076 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Tamoxifen or an Aromatase Inhibitor on Estrogen Metabolism in Women Treated for Newly Diagnosed Breast Cancer
NCT00569543 ·Status: COMPLETED
-
Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer
NCT02311933 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Tamoxifen in Treating Women With High-Risk Breast Cancer
NCT00002542 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Pharmacogenomics Differences in Phase I and II Metabolism of Tamoxifen on Efficacy and Toxicity
NCT00886535 ·Status: COMPLETED
-
Genotype and Phenotype Guided Supplementation of TAMoxifen Standard Therapy With ENDOXifen in Breast Cancer Patients
NCT03931928 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Tamoxifen on Breast Density in Premenopausal Women With Breast Cancer or High Risk for Breast Cancer
NCT00086749 ·Status: COMPLETED
-
SWOG-8814 Tamoxifen With or Without Combination Chemotherapy in Postmenopausal Women Who Have Undergone Surgery for Breast Cancer
NCT00929591 ·Status: COMPLETED ·Phase: PHASE3
-
Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast
NCT02993159 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Trial of Tamoxifen and 9-Cis-Retinoic Acid in Breast Cancer Patients
NCT00001504 ·Status: COMPLETED ·Phase: PHASE1
-
Trial of Low Dose Tamoxifen in Women With Breast Intraepithelial Neoplasia - Long Term Follow-up
NCT01357772 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Tamoxifen to Prevent Bone Loss and Heart Disease in Premenopausal Women Receiving Chemotherapy for Stage I or Stage II Breast Cancer
NCT00005605 ·Status: COMPLETED
-
Efficacy of Tamoxifen Versus Toremifene in CYP2D6 IM/PM of Premenopausal Patients With ER-positive Early Breast Cancer
NCT03351062 ·Status: RECRUITING ·Phase: PHASE3
-
Study Of MK-0752 In Combination With Tamoxifen Or Letrozole to Treat Early Stage Breast Cancer
NCT00756717 ·Status: COMPLETED ·Phase: PHASE4
-
4-Hydroxytamoxifen or Tamoxifen Citrate in Treating Women With Newly Diagnosed Ductal Breast Carcinoma in Situ
NCT00952731 ·Status: COMPLETED ·Phase: PHASE2
-
Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk
NCT04570956 ·Status: TERMINATED ·Phase: PHASE2
-
Breath Test for Women Receiving Tamoxifen in the Prevention or Treatment of Breast Cancer
NCT00873366 ·Status: TERMINATED
-
Dose-determining and Dose-confirmatory Study to Investigate the Optimal Dose of Tamoxifen in Breast Cancer Patients According to Genotype Status of TCF20 rs932376
NCT04961632 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Tamoxifen Citrate in Patients With Breast Cancer
NCT00963209 ·Status: UNKNOWN ·Phase: PHASE3
-
Tamoxifen for the Prevention of Breast Cancer in High-Risk Women
NCT00002644 ·Status: COMPLETED ·Phase: PHASE3
-
Testing Low Dose Tamoxifen for Invasive Breast Cancer, the (LoTam) Trial
NCT06671912 ·Status: SUSPENDED ·Phase: PHASE3
-
Anastrozole or Tamoxifen in Treating Postmenopausal Women With Ductal Carcinoma in Situ Who Are Undergoing Lumpectomy and Radiation Therapy
NCT00053898 ·Status: COMPLETED ·Phase: PHASE3
-
Octreotide, Tamoxifen, and Chemotherapy in Treating Women With Breast Cancer
NCT00002967 ·Status: COMPLETED ·Phase: PHASE3