MedTrace Logo

Treating Clozapine-induced Sinustachycardia With Bisoprolol

NCT00882856 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2017-01-09

No results posted yet for this study

Summary

Clozapine-induced sinustachycardia occurs in 25% of patients treated with clozapine and sustained sinustachycardia might be a risk factor for dilated cardiomyopathy. This double-blinded cross over placebo controlled study investigate whether 10 mg bisoprolol are efficient in treating clozapine-induced sinustachycardia measured as heart rate, heart rate variability, QTc and T-wave morphology.

Conditions

  • Clozapine-induced Sinustachycardia

Interventions

DRUG

Bisoprolol

Bisoprolol "Vitabalnas" 10 mg once daily

DRUG

Placebo

placebo

Sponsors & Collaborators

  • Aalborg University Hospital

    collaborator OTHER

  • Aalborg University

    collaborator OTHER

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Ole Schjerning, M.D. · Aalborg University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-04-30
Primary Completion
2016-12-31
Completion
2016-12-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00882856 on ClinicalTrials.gov