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Amino Acid and Acylcarnitine Profiles in Premature Neonates

NCT00865150 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1003

Last updated 2012-03-01

No results posted yet for this study

Summary

Primary Hypotheses of the study include:

* Metabolic profiles are influenced by gestational age, chronological age, type and degree of nutritional support and illness
* Metabolic profiles differ between neonates who receive commercial formula and neonates who receive primarily human breast milk
* Neonates who develop parenteral associated cholestasis have metabolic markers that identify at risk patients (high serum urea nitrogen, citrulline, histidine, methionine, and succinyl carnitine and low thyroxine, serine and glutamate)
* Neonates that have hypothyroidism have abnormal metabolic profiles (low tyrosine levels)

Conditions

  • Prematurity
  • Neonatal Screening
  • Parenteral Nutrition

Sponsors & Collaborators

  • Pediatrix

    lead OTHER

Principal Investigators

  • Reese Clark, MD · Pediatrix Medical Group, Inc.

Eligibility

Min Age
23 Weeks
Max Age
31 Weeks
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-04-30
Primary Completion
2011-08-31
Completion
2012-02-29

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00865150 on ClinicalTrials.gov