Allopurinol in Schizophrenia: A Randomized Trial Administering Allopurinol vs Placebo as add-on Antipsychotics in Patients With Schizophrenia
NCT00864825 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 248
Last updated 2012-05-08
Summary
The objective of the study is to evaluate the efficacy of allopurinol, compared to placebo, as add-on to anti-psychotics in the treatment of patients with schizophrenia.
Conditions
- Schizophrenia
- Schizoaffective Disorder
Interventions
- DRUG
-
Allopurinol
Allopurinol 1 capsule 300 mg, or placebo, bid (twice a day) for 42 days.
Sponsors & Collaborators
-
Sheba Medical Center
lead OTHER_GOV
Principal Investigators
-
Mark Weiser, MD · Sheba Medical Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-08-31
- Primary Completion
- 2009-12-31
- Completion
- 2010-01-31
Countries
- Israel
- Romania
Study Locations
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