Differential Immune Effects of Natalizumab
NCT00859482 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 27
Last updated 2009-03-11
Summary
Natalizumab is a humanized monoclonal antibody directed against Very Late Activation Antigene 4 (VLA-4) and has a potent effect on disease activity in multiple sclerosis (MS). A blockade of VLA-4 with natalizumab may not only interfere with autoimmunological processes but also with central nervous system (CNS) immune surveillance.
Conditions
- Multiple Sclerosis, Relapsing Remitting
Sponsors & Collaborators
-
Cantonal Hospital of St. Gallen
lead OTHER
Principal Investigators
-
Norman Putzki, MD · KSSG, 9007 St. Gallen, Switzerland
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-07-31
- Primary Completion
- 2007-07-31
- Completion
- 2007-07-31
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