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Azelastine Fluticasone Combination vs. Fluticasone

NCT00845598 · Status: WITHDRAWN · Phase: PHASE4 · Type: INTERVENTIONAL

Last updated 2012-06-12

No results posted yet for this study

Summary

The purpose of this study is to see how a combination spray of azelastine and fluticasone (antihistamine and steroid) compares with a steroid nasal spray (fluticasone) alone in allergic rhinitis i.e. does azelastine permit the use of lesser steroid dose (steroid sparing effect) to achieve the same benefit.

Conditions

  • Allergic Rhinitis

Interventions

DRUG

Azelastine , fluticasone

Azelastine Hydrochloride BP 0.10% w/v AND Fluticasone propionate BP 0.0357% w/v as combination 1 squirt in each nostril twice daily

DRUG

Fluticasone propionate

Fluticasone propionate 0.05% w/w 2 squirts in each nostril (50 μg per squirt)

Sponsors & Collaborators

  • University of Dundee

    lead OTHER

Principal Investigators

  • Sriram Vaidyanathan, MBBS · University of Dundee

  • Brian Lipworth, MD, FRCP · University of Dundee

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-08-31
Primary Completion
2011-08-31
Completion
2011-08-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00845598 on ClinicalTrials.gov