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Prolactin Receptor and Breast Diseases

NCT00842465 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 735

Last updated 2013-11-25

No results posted yet for this study

Summary

Prolactin is known to play an important role in breast development and differentiation. Thus proliferative breast diseases are good models to unravel PRl / PRLR function in proliferative processes.

The aim of this project is to identify and to characterize new mutants of the prolactin receptor gene within cohorts of benign or malign breast diseases with low or high occurrence frequency in human populations

Conditions

Interventions

BIOLOGICAL

blood collection for hormonal status analysis

for hormonal status analysis

PROCEDURE

breast Biopsy or surgery

breast Biopsy or surgery

GENETIC

blood collection

blood collection for prlR gene sequencing

OTHER

ultrasonography (pelvis and breast), bone mineral density

ultrasonography (pelvis and breast), bone mineral density

Sponsors & Collaborators

  • Institut Pasteur

    collaborator INDUSTRY

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Philippe Touraine, MD, PhD · Assistance Publique - Hôpitaux de Paris

Eligibility

Min Age
10 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-09-30
Primary Completion
2012-06-30
Completion
2012-06-30

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00842465 on ClinicalTrials.gov