Positive Lifestyles Using Safety

Summary

Project PLUS tests an HIV risk reduction/adherence behavioral intervention with HIV-infected individuals in Connecticut prisons. Participants are randomly assigned to one of three groups: prior to release from incarceration (Group 1), after release from incarceration (Group 2), and treatment-as-usual (Group 3). We hypothesize that the intervention groups (Groups 1 \& 2) will demonstrate significantly greater knowledge regarding drug- and sex- related HIV risk behavior and HIV medication adherence, greater motivation to reduce HIV risk behavior and improve HIV medication adherence, and enhanced skills for engaging in HIV risk reduction behavior and HIV medication adherence vs. the treatment-as-usual group. We will also compare these outcomes between Groups 1 and 2.

Conditions

• HIV
• HIV Infections

Interventions

BEHAVIORAL

Pre-Release (Group 1)

Participants in the pre-release intervention group will receive four sessions in the four-week period prior to release and will receive a comprehensive booster session four weeks after release.

BEHAVIORAL

Post-release (Group 2)

Participants in the post-release intervention group will receive one comprehensive introductory session four weeks before release and four sessions during the four-week period after release.

Sponsors & Collaborators

• Centers for Disease Control and Prevention

  collaborator FED

• National Institute on Drug Abuse (NIDA)

  collaborator NIH

• Yale AIDS Program

  collaborator UNKNOWN

• AIDS Project Hartford

  collaborator INDUSTRY

• Connecticut State, Department of Correction

  collaborator UNKNOWN

• Yale University

  lead OTHER

Principal Investigators

• Frederick Altice, MD · Yale University

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

FACTORIAL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2008-01-31

Primary Completion

2010-08-31

Completion

2010-08-31

Countries

• United States

Study Locations