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Cholera Toxin B Subunit (CTB) Administered by Mucosal Way in Healthy Adult Volunteer

NCT00820144 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-03-31

No results posted yet for this study

Summary

It is a biomedical research without direct individual benefit, exploring and comparing the mucosal immune response after oral, nasal and sublingual administration of B-subunit of non-toxic cholera toxin (CTB) in healthy adult volunteers.

Conditions

Interventions

BIOLOGICAL

CTB by nasal way

BIOLOGICAL

absorption of CTB by oral way

absorption of CTB by oral way

BIOLOGICAL

absorption of dukoral by oral way

absorption of dukoral by oral way

BIOLOGICAL

absorption of CTB by sublingual way

absorption of CTB by sublingual way

BIOLOGICAL

absorption of CTB by sublingual way

absorption of CTB by sublingual way

Sponsors & Collaborators

  • Centre Hospitalier Universitaire de Nice

    lead OTHER

Principal Investigators

  • Paul HOFMAN, Professor · Departement d'anatomo-pathologie, CHU de Nice

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-04-30
Primary Completion
2006-04-30
Completion
2007-02-28

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00820144 on ClinicalTrials.gov