Anti-Inflammatory Type II Monocyte Induction by Glatiramer Acetate (Copaxone) Treatment of Multiple Sclerosis
NCT00819195 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 17
Last updated 2013-10-08
Summary
The purpose of this study is to determine whether glatiramer acetate (Copaxone) will induce anti-inflammatory type II monocyte development during treatment of MS, and if these antigen presenting cells (APC) will promote Th2 and Treg differentiation of naïve T cells.
Conditions
Interventions
- DRUG
-
Glatiramer acetate
20 mg daily subcutaneous injection. Six-month duration.
Sponsors & Collaborators
-
National Multiple Sclerosis Society
collaborator OTHER -
Teva Neuroscience, Inc.
collaborator INDUSTRY -
University of California, San Francisco
lead OTHER
Principal Investigators
-
Scott S. Zamvil, M.D. Ph.D. · UCSF Department of Neurology
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-12-31
- Primary Completion
- 2012-09-30
- Completion
- 2012-09-30
Countries
- United States
Study Locations
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