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Tears Substitutions and Their Effects on Higher Order Aberrometery

NCT00812721 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2017-04-04

No results posted yet for this study

Summary

Hypothesis is that tear substitutions cause blur after they are instilled. The investigators will use aberrometry as a measurement over time after a tear formulation is used and try to determine if there are any measurable change in higher order aberrations between different tear formulations and how long it takes to return to pre-instillation measurements thus providing information on duration of the tear drop. 4 commercially available "dry eye" artificial tears formulations will be used and preservative saline will act as a control. The study will be conducted on subjects that do not have clinical evidence of dry eye syndrome to focus the data on the blur effects of the tear substitutions.

Conditions

  • Dry Eye Syndrome

Interventions

OTHER

Preservative Free Saline

One drop will be instilled into each eye once

OTHER

Optive

One drop will be instilled into each eye once

OTHER

Refresh Moderate/Severe

One drop will be instilled into each eye once

OTHER

Systane

One drop will be instilled into each eye once

OTHER

Systane Ultra

One drop will be instilled into each eye once

Sponsors & Collaborators

  • Gina Rogers

    lead OTHER

Principal Investigators

  • Gina M Rogers, MD · University of Iowa Department of Ophthalmology and Visual Sciences

  • Christine Sindt, OD · niversity of Iowa Department of Ophthalmology and Visual Sciences

Study Design

Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-01-31
Primary Completion
2009-06-30
Completion
2009-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00812721 on ClinicalTrials.gov