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Pilot Human Study of Tinidazole Efficacy For Radical Cure Of Plasmodium Vivax

NCT00811096 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2012-12-03

No results posted yet for this study

Summary

Assess the efficacy of 2 grams of tinidazole given for 5 days with standard dose chloroquine to achieve radical cure of Plasmodium vivax within a 90 day follow-up period sufficient to justify an IND and formal phase II evaluation.

Conditions

  • Malaria, Vivax

Interventions

DRUG

Tinidazole

2gms, p.o. q.d. for 5 days

DRUG

chloroquine

Sponsors & Collaborators

  • Walter Reed Army Institute of Research (WRAIR)

    lead FED

Principal Investigators

  • Francois Nosten, MD · Malaria Research Unit, Thailand

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-11-30
Primary Completion
2009-01-31
Completion
2009-04-30

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00811096 on ClinicalTrials.gov