Trial Outcomes & Findings for Prevention of Anthracycline or Trastuzumab Induced Cardiomyopathy by Metoprolol (NCT NCT00806390)

Last Updated: 2022-02-25

Results Overview

Because of the inability to enroll an adequate number of patients, (only 15 out of a planned 50) no data analysis was collected or performed.

Recruitment status

TERMINATED

Study phase

PHASE4

Target enrollment

15 participants

Primary outcome timeframe

Pre and post anthracycline treatment

Results posted on

2022-02-25

Participant milestones
Measure	Metoprolol Receiving metoprolol Metoprolol: Metroprolol tartrate titrated up	Control Not receiving metoprolol
Overall Study STARTED	7	8
Overall Study COMPLETED	7	8
Overall Study NOT COMPLETED	0	0

Withdrawal data not reported

Prevention of Anthracycline or Trastuzumab Induced Cardiomyopathy by Metoprolol

Baseline characteristics by cohort
Measure	Metoprolol n=7 Participants Receiving metoprolol Metoprolol: Metroprolol tartrate titrated up	Control n=8 Participants Not receiving metoprolol	Total n=15 Participants Total of all reporting groups
Age, Continuous	51 years STANDARD_DEVIATION 11 • n=99 Participants	47 years STANDARD_DEVIATION 8 • n=107 Participants	49 years STANDARD_DEVIATION 10 • n=206 Participants
Age, Categorical <=18 years	0 Participants n=99 Participants	0 Participants n=107 Participants	0 Participants n=206 Participants
Age, Categorical Between 18 and 65 years	7 Participants n=99 Participants	8 Participants n=107 Participants	15 Participants n=206 Participants
Age, Categorical >=65 years	0 Participants n=99 Participants	0 Participants n=107 Participants	0 Participants n=206 Participants
Sex: Female, Male Female	7 Participants n=99 Participants	8 Participants n=107 Participants	15 Participants n=206 Participants
Sex: Female, Male Male	0 Participants n=99 Participants	0 Participants n=107 Participants	0 Participants n=206 Participants
Region of Enrollment United States	7 participants n=99 Participants	8 participants n=107 Participants	15 participants n=206 Participants

Timeframe: Pre and post anthracycline treatment

Population: This study was unable to enroll a sufficient number of patients to permit analysis (only 15 patients enrolled)

Because of the inability to enroll an adequate number of patients, (only 15 out of a planned 50) no data analysis was collected or performed.

Outcome data not reported

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Adverse event data not reported

Adverse event data not reported

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