Trial Outcomes & Findings for An Open-Label Study Investigating the Effects of Early Skin Barrier Protection on the Development of Atopic Dermatitis (NCT NCT00806221)

NCT ID: NCT00806221

Last Updated: 2017-07-11

Results Overview

Recruitment status

COMPLETED

Study phase

PHASE2

Target enrollment

22 participants

Primary outcome timeframe

1 and 2 year time points

Results posted on

2017-07-11

Participant Flow

Participant milestones

Participant milestones
Measure
Emollient
Emollient (Cetaphil cream): Cetaphil cream applied daily from birth
Overall Study
STARTED
22
Overall Study
COMPLETED
20
Overall Study
NOT COMPLETED
2

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

An Open-Label Study Investigating the Effects of Early Skin Barrier Protection on the Development of Atopic Dermatitis

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Emollient
n=22 Participants
Skin barrier protection from birth emollient (Cetaphil cream): Cetaphil cream applied daily from birth
Age, Categorical
<=18 years
22 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=99 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
Sex/Gender, Customized
gender/sex was not recorded
22 participants
n=99 Participants
Race/Ethnicity, Customized
non-Hispanic Caucasian
16 Participants
n=99 Participants
Race/Ethnicity, Customized
Hispanic Caucasian
2 Participants
n=99 Participants
Race/Ethnicity, Customized
Asian
2 Participants
n=99 Participants
Race/Ethnicity, Customized
African American
2 Participants
n=99 Participants
Region of Enrollment
United States
22 participants
n=99 Participants

PRIMARY outcome

Timeframe: 1 and 2 year time points

Outcome measures

Outcome measures
Measure
Emollient
n=22 Participants
Emollient (Cetaphil cream): Cetaphil cream applied daily from birth
Incidence of Skin Irritation
0 Participants

PRIMARY outcome

Timeframe: 1 and 2 year timepoints

Outcome measures

Outcome measures
Measure
Emollient
n=22 Participants
Emollient (Cetaphil cream): Cetaphil cream applied daily from birth
Incidence of Skin Infection
0 Participants

PRIMARY outcome

Timeframe: over two years

Outcome measures

Outcome measures
Measure
Emollient
n=22 Participants
Emollient (Cetaphil cream): Cetaphil cream applied daily from birth
Compliance With Protocol
20 participants

SECONDARY outcome

Timeframe: 1 and 2 year time points

Outcome measures

Outcome measures
Measure
Emollient
n=22 Participants
Emollient (Cetaphil cream): Cetaphil cream applied daily from birth
Development of Eczema
5 Participants

Adverse Events

Emollient

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Eric Simpson, MD, MCR

Oregon Health & Science University

Phone: 503-494-2121

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place