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Protective Immunity Project 01

NCT00788021 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 124

Last updated 2013-11-25

No results posted yet for this study

Summary

Patients who undergo kidney transplant must take medications to prevent organ rejection. There are standard immunosuppressant medications such as prednisone, tacrolimus (Prograf), mycophenolate mofetil(Cellcept) or sirolimus (Rapamune) that are given to patients to prevent rejection. It is well known that patients on immunosuppressant medications are at increased risk from viral infections, such as influenza. However, it is not well understood how immunosuppressive medications may uniquely affect the immune response to infection. This study will determine whether there are unique differences in the effects on the immune system by these different immunosuppressive medications, particularly differences between tacrolimus and sirolimus.

Conditions

  • Kidney Transplantation
  • Immunity
  • Immunosuppression

Sponsors & Collaborators

  • Emory University

    lead OTHER

Principal Investigators

  • Christian P. Larsen, MD, DPhil · Emory University

  • Kenneth E. Kokko, MD, PhD · Emory University

Eligibility

Min Age
18 Years
Max Age
59 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-09-30
Primary Completion
2011-01-31
Completion
2011-10-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00788021 on ClinicalTrials.gov