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Comparison of Phenprocoumon and Acetylsalicylic Acid (ASA)

NCT00782743 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 157

Last updated 2015-09-23

No results posted yet for this study

Summary

In this open, prospective, non-randomised, parallel group, unicentric pilot-study will be compared the progress of valvular and coronary calcification with regard to the therapy with either acetyl-salicylic acid or phenprocoumon. The progress of calcification is documented by comparison of cardial stratified computed tomography. It is supposed that treatment with phenprocumon leads to increased coronary and valvular calcification as well to decreased blood levels of carboxylated matrix-GLA-protein

Conditions

  • Valvular Calcification
  • Coronary Calcification

Sponsors & Collaborators

  • RWTH Aachen University

    lead OTHER

Principal Investigators

  • Vincent Brandenburg, Prof. · RWTH Aachen University Departement of Cardiology, Pulmonology and Vascular Medicine

Eligibility

Min Age
50 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-02-29
Primary Completion
2015-08-31
Completion
2015-08-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00782743 on ClinicalTrials.gov