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Effect of Quetiapine XR on Sleep in Patients With Major Depression, as Compared With Mirtazapine

NCT00782405 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2011-04-19

No results posted yet for this study

Summary

The purpose of this study is to examine the effects of (a) quetiapine XR and (b) mirtazapine on sleep when given as an antidepressant (monotherapy). We hypothesize that (a) quetiapine XR has an immediate and lasting positive effect on sleep in depressed patients which does not differ from the impact of mirtazapine on sleep in this group of patients; (b) in the context of a secondary objective, we expect an antidepressant effect of quetiapine XR which is equivalent to that of mirtazapine.

Conditions

  • Sleep

Interventions

DRUG

quetiapine

XR, 150-300mg

DRUG

mirtazapine

30-45 mg

Sponsors & Collaborators

  • Technical University of Munich

    lead OTHER

Principal Investigators

  • Michael H Wiegand, Prof. · Sleep Disorders Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-10-31
Primary Completion
2011-04-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00782405 on ClinicalTrials.gov