Trial Outcomes & Findings for Side Effect Profiles of Brand Name Versus Generic Oral Contraceptives (NCT NCT00775190)

NCT ID: NCT00775190

Last Updated: 2017-04-17

Results Overview

Measures how light or heavy the menstrual flow on a 1 to 3 Likert scale. (Light, Medium, Heavy).

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

12 participants

Primary outcome timeframe

6 Months

Results posted on

2017-04-17

Participant Flow

Participant milestones

Participant milestones
Measure
Ortho Tricyclen™
ortho tricyclen: brand name oral contraceptive
Trinessa™
Trinessa: generic oral contraceptive
Overall Study
STARTED
7
5
Overall Study
COMPLETED
3
0
Overall Study
NOT COMPLETED
4
5

Reasons for withdrawal

Reasons for withdrawal
Measure
Ortho Tricyclen™
ortho tricyclen: brand name oral contraceptive
Trinessa™
Trinessa: generic oral contraceptive
Overall Study
Lost to Follow-up
2
3
Overall Study
Withdrawal by Subject
1
2
Overall Study
Protocol Violation
1
0

Baseline Characteristics

Side Effect Profiles of Brand Name Versus Generic Oral Contraceptives

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Ortho Tricyclen™
n=7 Participants
ortho tricyclen: brand name oral contraceptive
Trinessa™
n=5 Participants
Trinessa: generic oral contraceptive
Total
n=12 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Age, Categorical
Between 18 and 65 years
7 Participants
n=99 Participants
5 Participants
n=107 Participants
12 Participants
n=206 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Age, Continuous
24 years
n=99 Participants
24 years
n=107 Participants
24 years
n=206 Participants
Sex: Female, Male
Female
7 Participants
n=99 Participants
5 Participants
n=107 Participants
12 Participants
n=206 Participants
Sex: Female, Male
Male
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
Region of Enrollment
United States
7 participants
n=99 Participants
5 participants
n=107 Participants
12 participants
n=206 Participants

PRIMARY outcome

Timeframe: 6 Months

Population: Study Terminated with no data analysis.

Measures how light or heavy the menstrual flow on a 1 to 3 Likert scale. (Light, Medium, Heavy).

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 6 months

Population: Study Terminated with no data analysis

Any breakthrough bleeding during reporting period.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 6 months

Population: Study Terminated with no data analysis

Number of days with bleeding during each menstrual period.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 months

Population: Study Terminated with no data analysis

Number of days of nausea

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 Months

Population: Study Terminated with no data analysis

Number of episodes of vomitting

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 Months

Population: Study Terminated with no data analysis

Incidence of breast tenderness during the study time frame

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 months

Population: Study Terminated with no data analysis

Self reported changes in mood during each month over the time frame.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 months

Population: Study Terminated with no data analysis

Intensity of menstrual cramps reported on a 4 point Likert scale.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 months

Population: Study Terminated with no data analysis

Occurrence of any thromboembolic events during the study time frame.

Outcome measures

Outcome data not reported

Adverse Events

Ortho Tricyclen™

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Trinessa™

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Evie Russell, RN

Beaumont Health System

Phone: 248-898-5388

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place