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MOR and COMT SNP Polymorphism and Pain

NCT00773760 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2009-08-06

No results posted yet for this study

Summary

Patients with certain polymorphism in the MOR and COMT genes will display differences in their response to analgesics.

Conditions

  • Pain Relief

Interventions

OTHER

SNP genotyping

Coded blood specimens will be transported to the Department of Gene Technology TTÜ and genotyping analysis will be performed. Lymphocytes will be isolated from blood specimens using Ficol-Paq gradients, and genomic DNA isolated using a salting-out procedure. Variants of the MOR gene and other genes of interests will be performed by DNA sequence analysis of PCR-amplified DNA, using primers located in flanking intron sequence. All methods proposed are currently in operation in the respective facilities.

Sponsors & Collaborators

  • East Tallinn Central Hospital

    lead OTHER

Principal Investigators

  • Yuri Kolesnikov, MD PhD · ETCH

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-10-31
Primary Completion
2009-10-31
Completion
2009-12-31

Countries

  • Estonia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00773760 on ClinicalTrials.gov