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A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of ABT-333

NCT00768690 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2010-10-13

No results posted yet for this study

Summary

The purpose of this study is to determine multiple dose safety, tolerability and pharmacokinetics of ABT-333 under nonfasting conditions in healthy adult subjects, and to determine the effect of single dose administration of ketoconazole on steady state ABT-333 pharmacokinetics

Conditions

  • HCV Infection

Interventions

DRUG

ABT-333

Capsule, or powder drug substance from the capsule powder mixed in an alternate vehicle. For additional information refer to arm description.

DRUG

ketoconazole

Tablet, see arms for intervention description

DRUG

placebo

Capsule or powder drug substance from the capsule powder mixed in an alternative vehicle. For additional information refer to arm description.

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Masking
TRIPLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-10-31
Primary Completion
2009-02-28

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00768690 on ClinicalTrials.gov