MedTrace Logo

Influence of Hemodialysis on Endothel-Depending Dilatation of Peripheral Arteries

NCT00764192 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2009-01-13

No results posted yet for this study

Summary

An impairment of nitric oxide (NO) bioavailability is associated with endothelial dysfunction and may contribute to the excessive incidence of cardiovascular complication in chronic haemodialysis (HD) patients. It is not known whether cell-free hemoglobin limits nitric oxide bioavailability during HD.

Conditions

  • Hemodialysis

Interventions

PROCEDURE

blood sample

blood sample before and after a single HD

PROCEDURE

Flow-mediated dilation (FMD) before and after a single HD

measuring of the flow-mediated dilation using high-resolution ultrasound

Sponsors & Collaborators

  • Heinrich-Heine University, Duesseldorf

    collaborator OTHER

  • RWTH Aachen University

    lead OTHER

Principal Investigators

  • Christian Meyer, MD · RWTH Aachen University, Medical Clinic I

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-10-31
Primary Completion
2007-02-28
Completion
2007-10-31

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00764192 on ClinicalTrials.gov