Trial Outcomes & Findings for Clinical Study to Examine Brushing on Dental Implants (NCT NCT00762619)
NCT ID: NCT00762619
Last Updated: 2011-01-25
Results Overview
Modified Plaque Index (mPI)is a Dental plaque scale as follows 0 = No plaque, 1 = Separate flecks of plaque at the cervical margin;2 = Plaque can be seen by naked eye.3 = Abundance of soft matter. The lower the number the less plaque is present on the tooth.
COMPLETED
PHASE3
105 participants
3 months
2011-01-25
Participant Flow
subjects were recruited by the PI at the clinical site
subjects were screened for medical and oral health criteria and given the assigned study treatment to brush with for the next 6 months. Enrolled subjects all had 1 dental implant and 1 natural tooth identified and used for clinical data information.
Participant milestones
| Measure |
A - Fluoride Control
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Overall Study
STARTED
|
55
|
50
|
|
Overall Study
COMPLETED
|
55
|
50
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Clinical Study to Examine Brushing on Dental Implants
Baseline characteristics by cohort
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
Total
n=105 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
53 Participants
n=99 Participants
|
48 Participants
n=107 Participants
|
101 Participants
n=206 Participants
|
|
Age, Categorical
>=65 years
|
2 Participants
n=99 Participants
|
2 Participants
n=107 Participants
|
4 Participants
n=206 Participants
|
|
Age Continuous
|
54.71 years
STANDARD_DEVIATION 9.6 • n=99 Participants
|
55.22 years
STANDARD_DEVIATION 11.6 • n=107 Participants
|
54.95 years
STANDARD_DEVIATION 10.56 • n=206 Participants
|
|
Sex: Female, Male
Female
|
29 Participants
n=99 Participants
|
24 Participants
n=107 Participants
|
53 Participants
n=206 Participants
|
|
Sex: Female, Male
Male
|
26 Participants
n=99 Participants
|
26 Participants
n=107 Participants
|
52 Participants
n=206 Participants
|
|
Region of Enrollment
Israel
|
55 participants
n=99 Participants
|
50 participants
n=107 Participants
|
105 participants
n=206 Participants
|
PRIMARY outcome
Timeframe: 3 monthsModified Plaque Index (mPI)is a Dental plaque scale as follows 0 = No plaque, 1 = Separate flecks of plaque at the cervical margin;2 = Plaque can be seen by naked eye.3 = Abundance of soft matter. The lower the number the less plaque is present on the tooth.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Mombelli Plaque Index (mPI) for Natural Teeth
|
1.96 units on a scale
Standard Deviation 0.63
|
1.82 units on a scale
Standard Deviation 0.62
|
PRIMARY outcome
Timeframe: 6 monthsModified Plaque Index (mPI) is a Dental plaque scale as follows 0 = No plaque, 1 = Separate flecks of plaque at the cervical margin;2 = Plaque can be seen by naked eye.3 = Abundance of soft matter. The lower the number the less plaque is present on the tooth.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Mombelli Plaque Index (mPI) for Natural Teeth
|
2.05 units on a scale
Standard Deviation 0.59
|
1.73 units on a scale
Standard Deviation 0.68
|
PRIMARY outcome
Timeframe: 3 monthsModified Plaque Index (mPI) is a dental plaque scale as follows 0 = No plaque, 1 = Separate flecks of plaque at the cervical margin;2 = Plaque can be seen by naked eye.3 = Abundance of soft matter. The lower the number the less plaque is present on the tooth.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Mombelli Plaque Index (mPI) for Dental Implants
|
1.62 units on a scale
Standard Deviation 0.63
|
1.35 units on a scale
Standard Deviation 0.48
|
PRIMARY outcome
Timeframe: 6 monthsModified Plaque Index (mPI) is a dental plaque scale as follows 0 = No plaque, 1 = Separate flecks of plaque at the cervical margin;2 = Plaque can be seen by naked eye.3 = Abundance of soft matter. The lower the number the less plaque is present on the tooth.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Mombelli Plaque Index (mPI) for Dental Implants
|
1.71 units on a scale
Standard Deviation 0.56
|
1.45 units on a scale
Standard Deviation 0.53
|
PRIMARY outcome
Timeframe: 3 monthsGingivitis score(GI) is defined: 0 = Absence of inflammation,1 = Mild inflammation-slight change in color and little change in texture,2 = Moderate inflammation-moderate glazing,redness,edema \& hypertrophy,3 = Severe inflammation-marked redness and hypertrophy tendency for spontaneous bleeding. Each tooth is scored on 6 surfaces:mesio-facial;2)mid-facial;3)disto-facial;4)mesio-lingual;5)mid-lingualand 6)disto-lingual. A whole mouth score = adding all the GI scores \& dividing by the total of number of sites scored. 3rd molars and teeth with restorations or crowns will be excluded.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Löe-Silness Gingival Index Score (GI) - Natural Teeth
|
1.3 units on a scale
Standard Deviation 0.73
|
1.17 units on a scale
Standard Deviation 0.61
|
PRIMARY outcome
Timeframe: 6 monthsGingivitis score(GI) is defined: 0 = Absence of inflammation,1 = Mild inflammation-slight change in color and little change in texture,2 = Moderate inflammation-moderate glazing,redness,edema \& hypertrophy,3 = Severe inflammation-marked redness and hypertrophy tendency for spontaneous bleeding.Each tooth is scored on 6 surfaces:mesio-facial;2)mid-facial;3)disto-facial;4)mesio-lingual;5)mid-lingualand 6)disto-lingual. A whole mouth score = adding all the GI scores \& dividing by the total of number of sites scored. 3rd molars and teeth with restorations or crowns will be excluded.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Löe-Silness Gingival Index Score (GI) - Natural Teeth
|
1.29 units on a scale
Standard Deviation 0.79
|
1.01 units on a scale
Standard Deviation 0.8
|
PRIMARY outcome
Timeframe: 3 monthsGingivitis Score (GI) is defined: 0 = Absence of inflammation,1=Mild inflammation-slight change in color and little change in texture,2 = Moderate inflammation-moderate glazing,redness,edema \& hypertrophy,3 = Severe inflammation-marked redness and hypertrophy tendency for spontaneous bleeding. Each tooth is scored on 6 surfaces:mesio-facial;2)mid-facial;3)disto-facial;4)mesio-lingual;5)mid-lingualand 6)disto-lingual. A whole mouth score=adding all the GI scores \& dividing by the total of number of sites scored. 3rd molars and teeth with restorations or crowns will be excluded.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Löe-Silness Gingival Index Score (GI)- Dental Implants
|
1.27 units on a scale
Standard Deviation 0.67
|
1.12 units on a scale
Standard Deviation 0.63
|
PRIMARY outcome
Timeframe: 6 monthsGingivitis Score (GI) is defined: 0 = Absence of inflammation,1 = Mild inflammation-slight change in color and little change in texture,2 = Moderate inflammation-moderate glazing,redness,edema \& hypertrophy,3 = Severe inflammation-marked redness and hypertrophy tendency for spontaneous bleeding. Each tooth is scored on 6 surfaces:mesio-facial;2)mid-facial;3)disto-facial;4)mesio-lingual;5)mid-lingualand 6)disto-lingual. A whole mouth score=adding all the GI scores \& dividing by the total of number of sites scored. 3rd molars and teeth with restorations or crowns will be excluded.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Löe-Silness Gingival Index Score (GI)- Dental Implants
|
1.24 units on a scale
Standard Deviation 0.81
|
0.99 units on a scale
Standard Deviation 0.73
|
PRIMARY outcome
Timeframe: 3 monthsSulcus bleeding index for teeth is explained here. Gums around teeth are scored:0 = gingiva of normal texture \& color, no bleeding;1 = gingiva normal, bleeds on probing;2 = bleeding on probing,change in color, no oedema; 3 = bleeding on probing,change in color, slight oedema;4 = bleeding on probing, change in color, obvious oedema;5=bleeding on probing, spontaneous bleeding, change in color, marked oedema.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Gingival Bleeding on Probing (BOP) Using Sulcus Bleeding Index for Teeth
|
0.77 Units on a scale
Standard Deviation 0.8
|
0.51 Units on a scale
Standard Deviation 0.67
|
PRIMARY outcome
Timeframe: 6 monthsSulcus bleeding index for teeth is explained here. Gums around teeth are scored:0 = gingiva of normal texture \& color, no bleeding;1 = gingiva normal, bleeds on probing;2 = bleeding on probing,change in color, no oedema;3 = bleeding on probing,change in color, slight oedema;4 = bleeding on probing,change in color, obvious oedema;5 = bleeding on probing, spontaneous bleeding,change in color,marked oedema.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Gingival Bleeding on Probing (BOP) Using Sulcus Bleeding Index for Teeth
|
0.877 Units on a scale
Standard Deviation 0.88
|
0.53 Units on a scale
Standard Deviation 0.76
|
PRIMARY outcome
Timeframe: 3 monthsGingival bleeding on probing (BOP) using the modified sulcus bleeding index for implants. Scale equals 0 = No bleeding when periodontal probe is passed along the gingival margin;1 = Isolated bleeding spots visible;2 = Blood forms a confluent red line on the gingival margin;3 = Heavy or profuse bleeding.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Gingival Bleeding on Probing (BOP) Using the Modified Sulcus Bleeding Index for Implants
|
0.65 Units on a scale
Standard Deviation 0.78
|
0.48 Units on a scale
Standard Deviation 0.68
|
PRIMARY outcome
Timeframe: 6 monthsGingival bleeding on probing (BOP) using the modified sulcus bleeding index for implants. Scale equals 0 = No bleeding when periodontal probe is passed along the gingival margin;1 = Isolated bleeding spots visible;2 = Blood forms a confluent red line on the gingival margin;3 = Heavy or profuse bleeding.
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Gingival Bleeding on Probing (BOP) Using the Modified Sulcus Bleeding Index for Implants
|
0.81 Units on a scale
Standard Deviation 0.9
|
0.45 Units on a scale
Standard Deviation 0.69
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are Least means square (LSM)determined by baseline adjusted means including Standard Error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
A.Actinomycetemcomitans (DNA Probe Analysis) - Natural Teeth
|
6.269 Log cfu (Colony Forming Units)
Standard Error 0.006
|
5.002 Log cfu (Colony Forming Units)
Standard Error 0.1117
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data point is Least means square (LSM) determined by baseline adjusted means including Standard Error of Means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
A.Actinomycetemcomitans (DNA Probe Analysis)- Natural Teeth
|
6.201 Log cfu (colony forming units)
Standard Error 0.1117
|
4.669 Log cfu (colony forming units)
Standard Error 0.1325
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implant. Data point is Least means square (LSM) determined by baseline adjusted means including Standard Error of Means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
A.Actinomycetemcomitans (DNA Probe Analysis)- Dental Implant
|
5.814 Log cfu (colony forming units)
Standard Error 0.1262
|
4.446 Log cfu (colony forming units)
Standard Error 0.1589
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implant. Data point is Least means square (LSM) determined by baseline adjusted means including Standard Error of Means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
A.Actinomycetemcomitans (DNA Probe Analysis)- Dental Implant
|
5.664 Log cfu (colony forming units)
Standard Error 0.1222
|
4.339 Log cfu (colony forming units)
Standard Error 0.1908
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
C.Rectus (DNA Probe Analysis) - Natural Teeth
|
4.69 Log cfu (colony forming units)
Standard Error 0.1269
|
3.322 Log cfu (colony forming units)
Standard Error 0.1548
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
C.Rectus (DNA Probe Analysis) - Natural Teeth
|
4.578 Log cfu (colony forming units)
Standard Error 0.1403
|
2.798 Log cfu (colony forming units)
Standard Error 0.172
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
C.Rectus (DNA Probe Analysis) - Dental Implant
|
4.46 Log cfu (colony forming units)
Standard Error 0.1226
|
3.015 Log cfu (colony forming units)
Standard Error 0.1843
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
C.Rectus (DNA Probe Analysis) - Dental Implant
|
4.318 Log cfu (colony forming units)
Standard Error 0.1318
|
2.758 Log cfu (colony forming units)
Standard Error 0.2106
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Capnocytophaga sp. (DNA Probe Analysis) - Natural Teeth
|
4.676 Log cfu (colony forming units)
Standard Error 0.05921
|
4.526 Log cfu (colony forming units)
Standard Error 0.06476
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Capnocytophaga sp. (DNA Probe Analysis) - Natural Teeth
|
4.644 Log cfu (colony forming units)
Standard Error 0.07209
|
4.411 Log cfu (colony forming units)
Standard Error 0.07971
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Capnocytophaga sp. (DNA Probe Analysis) - Dental Implant
|
4.391 Log cfu (colony forming units)
Standard Error 0.07532
|
4.243 Log cfu (colony forming units)
Standard Error 0.08163
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Capnocytophaga sp. (DNA Probe Analysis) - Dental Implant
|
4.356 Log cfu (colony forming units)
Standard Error 0.07716
|
4.268 Log cfu (colony forming units)
Standard Error 0.08752
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM)determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
E.Corrodens (DNA Probe Analysis) - Natural Teeth
|
6.47 Log cfu (colony forming units)
Standard Error 0.1477
|
5.822 Log cfu (colony forming units)
Standard Error 0.1583
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM)determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
E.Corrodens (DNA Probe Analysis) - Natural Teeth
|
6.417 Log cfu (colony forming units)
Standard Error 0.1808
|
5.682 Log cfu (colony forming units)
Standard Error 0.1937
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM)determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
E.Corrodens (DNA Probe Analysis) - Dental Implant
|
6.21 Log cfu (colony forming units)
Standard Error 0.148
|
5.639 Log cfu (colony forming units)
Standard Error 0.162
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM)determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
E.Corrodens (DNA Probe Analysis) - Dental Implant
|
6.242 Log cfu (colony forming units)
Standard Error 0.1619
|
5.482 Log cfu (colony forming units)
Standard Error 0.1791
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
E.Saburreum (DNA Probe Analysis) - Natural Teeth
|
5.229 Log cfu (colony forming units)
Standard Error 0.1199
|
4.385 Log cfu (colony forming units)
Standard Error 0.1328
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM)detemined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
E.Saburreum (DNA Probe Analysis)- Natural Teeth
|
5.079 Log cfu (colony forming units)
Standard Error 0.1424
|
3.571 Log cfu (colony forming units)
Standard Error 0.1655
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
E.Saburreum (DNA Probe Analysis) - Dental Implant
|
5.012 Log cfu (colony forming units)
Standard Error 0.1065
|
3.861 Log cfu (colony forming units)
Standard Error 0.1222
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
E.Saburreum (DNA Probe Analysis) - Dental Implant
|
4.733 Log cfu (colony forming units)
Standard Error 0.1287
|
3.372 Log cfu (colony forming units)
Standard Error 0.1728
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM)determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
F.Nucleatum (DNA Probe Analysis) - Natural Teeth
|
5.337 Log cfu (colony forming units)
Standard Error 0.1773
|
4.403 Log cfu (colony forming units)
Standard Error 0.123
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error of means (SEM)
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
F.Nucleatum (DNA Probe Analysis) - Natural Teeth
|
5.243 Log cfu (colony forming units)
Standard Error 0.1265
|
3.405 Log cfu (colony forming units)
Standard Error 0.1327
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM)determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
F.Nucleatum (DNA Probe Analysis) - Dental Implants
|
4.89 Log cfu (colony forming units)
Standard Error 0.1277
|
3.637 Log cfu (colony forming units)
Standard Error 0.1354
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM)determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
F.Nucleatum (DNA Probe Analysis) - Dental Implants
|
4.602 Log cfu (colony forming units)
Standard Error 0.1348
|
2.425 Log cfu (colony forming units)
Standard Error 0.1474
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Neissera sp. (DNA Probe Analysis) - Natural Teeth
|
4.638 Log cfu (colony forming units)
Standard Error 0.1203
|
4.508 Log cfu (colony forming units)
Standard Error 0.1336
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points least means square (LSM) determined by baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Neissera sp. (DNA Probe Analysis) Natural Teeth
|
4.702 Log cfu (colony forming units)
Standard Error 0.1301
|
4.658 Log cfu (colony forming units)
Standard Error 0.1604
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Neissera sp. (DNA Probe Analysis) - Dental Implants
|
4.405 Log cfu (colony forming units)
Standard Error 0.1151
|
3.955 Log cfu (colony forming units)
Standard Error 0.1193
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Neissera sp. (DNA Probe Analysis) - Dental Implants
|
4.585 Log cfu (colony forming units)
Standard Error 0.1546
|
4.415 Log cfu (colony forming units)
Standard Error 0.2199
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error of means (SEM)
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Gingivalis (DNA Probe Analysis) - Natural Teeth
|
6.166 Log cfu (colony forming units)
Standard Error 0.1438
|
5.183 Log cfu (colony forming units)
Standard Error 0.1705
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM)
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Gingivalis (DNA Probe Analysis) - Natural Teeth
|
6.071 Log cfu (colony forming units)
Standard Error 0.1675
|
4.951 Log cfu (colony forming units)
Standard Error 0.2125
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error of means (SEM)
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Gingivalis (DNA Probe Analysis) - Dental Implants
|
5.784 Log cfu (colony forming units)
Standard Error 0.1533
|
4.926 Log cfu (colony forming units)
Standard Error 0.1789
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error of means (SEM)
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Gingivalis (DNA Probe Analysis) - Dental Implants
|
5.562 Log cfu (colony forming units)
Standard Error 0.1995
|
4.642 Log cfu (colony forming units)
Standard Error 0.2578
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Intermedia (DNA Probe Analysis) - Natural Teeth
|
5.091 Log cfu (colony forming units)
Standard Error 0.1526
|
3.853 Log cfu (colony forming units)
Standard Error 0.1824
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Intermedia (DNA Probe Analysis) - Natural Teeth
|
5.007 Log cfu (colony forming units)
Standard Error 0.1499
|
3.803 Log cfu (colony forming units)
Standard Error 0.1875
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Intermedia (DNA Probe Analysis) - Dental Implants
|
4.544 Log cfu (colony forming units)
Standard Error 0.1555
|
3.853 Log cfu (colony forming units)
Standard Error 0.2115
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Intermedia (DNA Probe Analysis) - Dental Implants
|
4.329 Log cfu (colony forming units)
Standard Error 0.1617
|
3.803 Log cfu (colony forming units)
Standard Error 0.3178
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Melaninogenica (DNA Probe Analysis) - Natural Teeth
|
5.066 Log cfu (colony forming units)
Standard Error 0.1067
|
3.935 Log cfu (colony forming units)
Standard Error 0.1171
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for both natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Melaninogenica (DNA Probe Analysis) - Natural Teeth
|
5.062 Log cfu (colony forming units)
Standard Error 0.1141
|
3.691 Log cfu (colony forming units)
Standard Error 0.1252
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Melaninogenica (DNA Probe Analysis) - Dental Implants
|
4.406 Log cfu (colony forming units)
Standard Error 0.0982
|
3.363 Log cfu (colony forming units)
Standard Error 0.11309
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
P.Melaninogenica (DNA Probe Analysis) - Dental Implants
|
4.387 Log cfu (colony forming units)
Standard Error 0.1131
|
3.155 Log cfu (colony forming units)
Standard Error 0.1303
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Solobacterium (S.Moorei)(DNA Probe Analysis) - Natural Teeth
|
6.511 Log cfu (colony forming units)
Standard Error 0.1553
|
5.237 Log cfu (colony forming units)
Standard Error 0.1608
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Solobacterium (S.Moorei)(DNA Probe Analysis) - Natural Teeth
|
6.081 Log cfu (colony forming units)
Standard Error 0.2425
|
4.487 Log cfu (colony forming units)
Standard Error 0.2476
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Solobacterium (S.Moorei)(DNA Probe Analysis) - Dental Implants
|
5.767 Log cfu (colony forming units)
Standard Error 0.0346
|
4.701 Log cfu (colony forming units)
Standard Error 0.02777
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Solobacterium (S.Moorei)(DNA Probe Analysis) - Dental Implants
|
5.046 Log cfu (colony forming units)
Standard Error 0.3545
|
3.899 Log cfu (colony forming units)
Standard Error 0.4863
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means )SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Streptococci (DNA Probe Analysis) - Natural Teeth
|
5.995 Log cfu (colony forming units)
Standard Error 0.1175
|
4.495 Log cfu (colony forming units)
Standard Error 0.1234
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Streptococci (DNA Probe Analysis) - Natural Teeth
|
5.867 Log cfu (colony forming units)
Standard Error 0.1195
|
4.109 Log cfu (colony forming units)
Standard Error 0.1255
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means )SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Streptococci (DNA Probe Analysis) - Dental Implants
|
5 Log cfu (colony forming units)
Standard Error 0.1317
|
3.263 Log cfu (colony forming units)
Standard Error 0.1383
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means )SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Streptococci (DNA Probe Analysis) - Dental Implants
|
4.665 Log cfu (colony forming units)
Standard Error 0.1431
|
2.404 Log cfu (colony forming units)
Standard Error 0.1503
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for both natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
T.Forsythia (DNA Probe Analysis)- Natural Teeth
|
6.408 Log cfu (colony forming units)
Standard Error 0.1348
|
5.143 Log cfu (colony forming units)
Standard Error 0.1474
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
T.Forsythia (DNA Probe Analysis)-Natural Teeth
|
6.286 Log cfu (colony forming units)
Standard Error 0.1628
|
4.926 Log cfu (colony forming units)
Standard Error 0.182
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for both Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
T.Forsythia (DNA Probe Analysis)- Dental Implants
|
6.19 Log cfu (colony forming units)
Standard Error 0.1637
|
4.628 Log cfu (colony forming units)
Standard Error 0.1831
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for both Dental Implants. Data points are least means square (LSM) determined by using baseline adjusted means including standard error of means (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
T.Forsythia (DNA Probe Analysis)- Dental Implants
|
6.08 Log cfu (colony forming units)
Standard Error 0.1691
|
4.633 Log cfu (colony forming units)
Standard Error 0.2153
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error (SEM)
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Veillonella sp.(DNA Probe Analysis) - Natural Teeth
|
5.82 Log cfu (colony forming units)
Standard Error 0.1185
|
4.927 Log cfu (colony forming units)
Standard Error 0.1245
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for natural teeth. Data points are least means square (LSM) determined by using baseline adjusted means including standard error (SEM).
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Veillonella sp.(DNA Probe Analysis) - Natural Teeth
|
5.746 Log cfu (colony forming units)
Standard Error 0.1282
|
4.563 Log cfu (colony forming units)
Standard Error 0.1346
|
PRIMARY outcome
Timeframe: 3 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error (SEM)
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Veillonella sp.(DNA Probe Analysis) - Dental Implants
|
5.472 Log cfu (colony forming units)
Standard Error 0.1408
|
4.485 Log cfu (colony forming units)
Standard Error 0.1494
|
PRIMARY outcome
Timeframe: 6 months14 microorganisms were identified via DNA probe analysis for Dental Implants. Data points are least means square (LSM) detemined by using baseline adjusted means including standard error (SEM)
Outcome measures
| Measure |
A - Fluoride Control
n=55 Participants
Fluoride toothpaste (Ultrabrite)group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
B - Postive Control
n=50 Participants
fluoride/triclosan/copolymer toothpaste group contained both 1 natural tooth site and 1 dental implant site for clinical assessment.
|
|---|---|---|
|
Veillonella sp.(DNA Probe Analysis) - Dental Implants
|
5.364 Log cfu (colony forming units)
Standard Error 0.1425
|
4.186 Log cfu (colony forming units)
Standard Error 0.1511
|
Adverse Events
A - Fluoride Control
B - Postive Control
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place
Restriction type: LTE60