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Total Knee Arthroplasty And Thromboembolism: A Comparison Between Two Surgical Techniques

NCT00755300 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2011-08-15

No results posted yet for this study

Summary

In patients undergoing total knee arthroplasty, thromboembolism is a common occurrence, especially following tourniquet deflation. The resulting cardiopulmonary emboli can potentially lead to hypoxemia, hypotension, hemodynamic collapse and post operative cognitive dysfunction due to emboli. The standard surgical technique involves placing an intramedullary rod in the femur to determine the angle and degree of resection from the end of the femur. A new surgical technique utilizes computer navigation system to perform the desired cuts in the appropriate position. The investigators hypothesize that the avoidance of intramedullary instrumentation in computer assisted total knee replacement will result in fewer thromboembolic events compared with the standard technique using manual instrumentation in the femur. The present study will test this hypothesis by quantifying the extent of thromboembolism during both surgical techniques.

Conditions

  • Total Knee Replacement
  • Venous Thromboembolism

Interventions

PROCEDURE

Measurement of total thrombolic load

A video recording of the right atrium using TE echo will be used to quantitate the total thromboembolic load

Sponsors & Collaborators

  • University of California, Davis

    lead OTHER

Principal Investigators

  • Amrik Singh, M.D. · Associate Professor, Cardiovascular and Thoracic Anesthesiology, UC Davis, Department of Anesthesiology and Pain Medicine

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-06-30
Primary Completion
2008-06-30
Completion
2009-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00755300 on ClinicalTrials.gov