Narrow-Band UVB-Therapy in Psoriasis
NCT00748020 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 109
Last updated 2008-09-08
Summary
Study on two different irradiation schemes in UVB phototherapy for psoriasis. Previous studies demonstrated a similar clinical effect in erythematogenic and suberythematogenic irradiation, with less complications in suberythematogenic irradiation. Most of these studies used both irradiation schemes within the same patient. UVB has a systemic effect on the body. Our hypothesis is that previous conclusions are incorrect and that the erythematogenic scheme will result in earlier clearance of the psoriasis.
Conditions
Interventions
- PROCEDURE
-
UVB phototherapy
Group 1: every irradiation an increase of 40%, starting with 70% of the minimal erythema dose
- PROCEDURE
-
UVB phototherapy
Group 2: every irradiation an increase of 20%, starting with 30% of the minimal erythema dose
Sponsors & Collaborators
-
Radboud University Medical Center
lead OTHER
Principal Investigators
-
Rianne Gerritsen, MD, PhD · Radboud University Medical Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2003-01-31
- Primary Completion
- 2006-05-31
- Completion
- 2007-01-31
Countries
- Netherlands
Study Locations
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