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Platelet-activating Factor Acetylhydrolase (Paf-ah) Gene Expression

NCT00747240 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 139

Last updated 2015-05-12

No results posted yet for this study

Summary

This is a prospective observational study to determine whether there is an association between the presence of platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphisms and the development of chronic lung disease in very low birth wight infants. Infants \< 1500 grams at birth who require mechanical ventilation will be enrolled in the first 5 days of life after obtaining informed consent. A total of 1 ml of blood will be drawn and utilized for isolation of DNA for genotyping and for measurement of PAF-AH activity in serum.

Conditions

  • Low Birth Weight Infant

Sponsors & Collaborators

Principal Investigators

  • Christian C Yost, M.D. · University of Utah

Eligibility

Max Age
5 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-02-28
Primary Completion
2014-12-31
Completion
2014-12-31

Countries

  • United States

Study Locations

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Entities

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00747240 on ClinicalTrials.gov