Heart Rate, Baroreflex Sensitivity and Cardiovascular Morbidity and Mortality in the Population

NCT00741728 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 10157

Last updated 2026-02-11

No results posted yet for this study

Summary

The aim of the present Paris Prospective Study III (PPS3) is (1) to assess the determinants of the regulation of heart rate and blood pressure variations and carotid properties (under different physiologic stimulations) and (2) to evaluate the respective contribution of heart rate, blood pressure variations and carotid properties to cardiovascular morbidity and mortality including sudden death during 10 years at least in healthy considered subjects.

Conditions

Interventions

OTHER

Spider flash ECG, high-precision carotid echo-tracking, step test

cardiac rhythm recorded during health check up, vascular aging parameters and baroreflex sensitivity recorded during carotid echotracking of the right common carotid artery , step test during 2 minutes

Sponsors & Collaborators

  • Institut National de la Santé Et de la Recherche Médicale, France

    lead OTHER_GOV

Principal Investigators

  • Xavier Jouven, MD, PhD · INSERM and APHP

  • Jean-Philippe Empana, MD, PhD · Institut National de la Santé Et de la Recherche Médicale, France

  • Pierre Boutouyrie, MD, PhD · INSERM and APHP

Eligibility

Min Age
50 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-05-13
Primary Completion
2032-06-30
Completion
2032-12-31

Countries

  • France

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00741728 on ClinicalTrials.gov