Heart Rate, Baroreflex Sensitivity and Cardiovascular Morbidity and Mortality in the Population
NCT00741728 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 10157
Last updated 2026-02-11
Summary
The aim of the present Paris Prospective Study III (PPS3) is (1) to assess the determinants of the regulation of heart rate and blood pressure variations and carotid properties (under different physiologic stimulations) and (2) to evaluate the respective contribution of heart rate, blood pressure variations and carotid properties to cardiovascular morbidity and mortality including sudden death during 10 years at least in healthy considered subjects.
Conditions
- Community Based Study
- Cardiovascular Disease
- Sudden Death
- Blood Pressure
Interventions
- OTHER
-
Spider flash ECG, high-precision carotid echo-tracking, step test
cardiac rhythm recorded during health check up, vascular aging parameters and baroreflex sensitivity recorded during carotid echotracking of the right common carotid artery , step test during 2 minutes
Sponsors & Collaborators
-
Institut National de la Santé Et de la Recherche Médicale, France
lead OTHER_GOV
Principal Investigators
-
Xavier Jouven, MD, PhD · INSERM and APHP
-
Jean-Philippe Empana, MD, PhD · Institut National de la Santé Et de la Recherche Médicale, France
-
Pierre Boutouyrie, MD, PhD · INSERM and APHP
Eligibility
- Min Age
- 50 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-05-13
- Primary Completion
- 2032-06-30
- Completion
- 2032-12-31
Countries
- France
Study Locations
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