Trial Outcomes & Findings for Oral Progesterone and Low Dose Aspirin in the Prevention of Preeclampsia (NCT NCT00719537)

NCT ID: NCT00719537

Last Updated: 2017-04-17

Results Overview

Number of Participants with preeclampsia in second and third trimester of pregnancy.

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

3 participants

Primary outcome timeframe

second and third trimester of pregnancy

Results posted on

2017-04-17

Participant Flow

Participant milestones

Participant milestones
Measure
Aspirin and Placebo
Aspirin and placebo: Aspirin 81mg once daily and placebo once daily
Aspirin and Progesterone
aspirin 81 mg once a day oral progesterone 200mg twice daily
Overall Study
STARTED
2
1
Overall Study
COMPLETED
1
0
Overall Study
NOT COMPLETED
1
1

Reasons for withdrawal

Reasons for withdrawal
Measure
Aspirin and Placebo
Aspirin and placebo: Aspirin 81mg once daily and placebo once daily
Aspirin and Progesterone
aspirin 81 mg once a day oral progesterone 200mg twice daily
Overall Study
Withdrawal by Subject
1
0
Overall Study
Lost to Follow-up
0
1

Baseline Characteristics

Oral Progesterone and Low Dose Aspirin in the Prevention of Preeclampsia

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Aspirin and Placebo
n=2 Participants
Aspirin and placebo: Aspirin 81mg once daily and placebo once daily
Aspirin and Progesterone
n=1 Participants
aspirin 81 mg once a day oral progesterone 200mg twice daily
Total
n=3 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=39 Participants
0 Participants
n=41 Participants
0 Participants
n=35 Participants
Age, Categorical
Between 18 and 65 years
2 Participants
n=39 Participants
1 Participants
n=41 Participants
3 Participants
n=35 Participants
Age, Categorical
>=65 years
0 Participants
n=39 Participants
0 Participants
n=41 Participants
0 Participants
n=35 Participants
Sex: Female, Male
Female
2 Participants
n=39 Participants
1 Participants
n=41 Participants
3 Participants
n=35 Participants
Sex: Female, Male
Male
0 Participants
n=39 Participants
0 Participants
n=41 Participants
0 Participants
n=35 Participants
Region of Enrollment
United States
2 participants
n=39 Participants
1 participants
n=41 Participants
3 participants
n=35 Participants

PRIMARY outcome

Timeframe: second and third trimester of pregnancy

Population: 1 Participant withdrawn in aspirin and placebo group, one participant lost to followup in aspirin and progesterone group.

Number of Participants with preeclampsia in second and third trimester of pregnancy.

Outcome measures

Outcome measures
Measure
Aspirin and Placebo
n=1 Participants
Aspirin and placebo: Aspirin 81mg once daily and placebo once daily
Aspirin and Progesterone
aspirin 81 mg once a day oral progesterone 200mg twice daily
Incidence of Preeclampsia
0 Participants

Adverse Events

Aspirin and Placebo

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Aspirin and Progesterone

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

John Uckele

William Beaumont Hospital

Phone: 2485510610

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place