Phase 3 Study of the Biologic Lung Volume Reduction (BLVR) System in Advanced Upper Lobe Predominant (ULP) Emphysema
NCT00716053 · Status: WITHDRAWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 225
Last updated 2010-01-18
Summary
The purpose of the study is to evaluate the efficacy and safety of the 20 mL BLVR System in treating patients with advanced upper lobe predominant emphysema.
Conditions
- Advanced Upper Lobe Predominant Emphysema
Interventions
- DRUG
-
BLVR
BLVR 20 mL
Sponsors & Collaborators
-
Aeris Therapeutics
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Sex
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-12-31
- Primary Completion
- 2009-12-31
- Completion
- 2009-12-31
More Related Trials
-
Israeli 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation
NCT00205907 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Netherlands 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation
NCT00205920 ·Status: TERMINATED ·Phase: PHASE2
-
Israeli Biologic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study
NCT00517998 ·Status: COMPLETED ·Phase: PHASE1
-
A Continuation Study of the AeriSeal® System Administered at 3 to 4 Sites During a Single Treatment Session for Lung Volume Reduction in Patients With Advanced Emphysema
NCT01320566 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Study of the AeriSeal System for HyPerInflation Reduction in Emphysema (ASPIRE)
NCT01449292 ·Status: TERMINATED ·Phase: PHASE3
-
AeriSeal® System for Lung Volume Reduction in Patients With Advanced Emphysema
NCT01181466 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Study of the AeriSeal System Treatment in Patients With Advanced Non-Upper Lobe Predominant Heterogeneous Emphysema
NCT01908933 ·Status: WITHDRAWN ·Phase: PHASE3
-
Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema
NCT05897424 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS)
NCT07135284 ·Status: RECRUITING
-
The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
NCT06872892 ·Status: RECRUITING ·Phase: PHASE3
-
A Study to Investigate Using Inhaled Fexlamose to Treat Adult Participants Who Have Moderate to Severe COPD
NCT06731959 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Bronchoscopic Lung Volume Reduction in Management of Localized Emphysema
NCT06629558 ·Status: RECRUITING ·Phase: NA
-
A Study to Test Whether Different Doses of BI 1291583 Help People With Bronchiectasis
NCT05238675 ·Status: COMPLETED ·Phase: PHASE2
-
Single and Multiple Ascending Dose Study of AER-01
NCT05862623 ·Status: UNKNOWN ·Phase: PHASE1
-
Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant
NCT05654922 ·Status: RECRUITING ·Phase: PHASE3
-
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
NCT07201051 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This Medicine
NCT05846230 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
First in Human Study to Assess an Implant to Treat Severe Emphysema
NCT05854550 ·Status: COMPLETED ·Phase: NA
-
A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems
NCT07023354 ·Status: RECRUITING ·Phase: PHASE1
-
Study of the Effect of FLUTTER® VRP1 (PEP and Oscillating High Frequency).
NCT01209546 ·Status: TERMINATED ·Phase: PHASE1
-
Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema
NCT05856331 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 1/Phase 2a Study of AERO-007 Inhalation Solution, a Nebulized LABA/LAMA Combination for Maintenance Treatment of COPD
NCT06841640 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Multi Center Study Testing a New Implant for Adults With Severe Emphysema
NCT07119229 ·Status: RECRUITING ·Phase: NA
-
Safety, Tolerability and Pharmacokinetic Study of LTI-03 in Healthy Adult Subjects
NCT04233814 ·Status: COMPLETED ·Phase: PHASE1
-
Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis
NCT07230288 ·Status: RECRUITING ·Phase: PHASE2