Effect of Oral Sildenafil With Digital Therapeutic Iontophoresis of Sodium Nitroprussiate in Healthy Volunteers
NCT00710099 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2011-10-06
Summary
Iontophoresis is a employed to facilitate drug absorption without systemic effect. This study investigates cutaneous microcirculation when we associate sildenafil per os with SNP via iontophoresis.
Conditions
- Healthy
Interventions
- DRUG
-
sildenafil
systemic absorption of sildenafil
- DRUG
-
nitroprussiate iontophoresis
nitroprussiate iontophoresis
Sponsors & Collaborators
-
University Hospital, Grenoble
lead OTHER
Principal Investigators
-
Jean-Luc CRACOWSKI, MD · Institut National de la Santé Et de la Recherche Médicale, France
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-07-31
- Primary Completion
- 2011-06-30
- Completion
- 2011-06-30
Countries
- France
Study Locations
More Related Trials
-
Acute Effects of Sildenafil on Endothelial Function in People With Diabetes
NCT00527995 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Regular Sildenafil on Blood Pressure and Arterial Function in Hypertension
NCT00317421 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Compare the Blood Levels of Sildenafil Following Administration of an Experimental Tablet vs. the Conventional Oral Tablet in Healthy Subjects.
NCT00795938 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Given With Or Without Food.
NCT01254396 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Sildenafil Citrate on Uteri- Placental Perfusion, Doppler Indices in Growth Restricted Fetuses
NCT02362399 ·Status: COMPLETED ·Phase: NA
-
Effects of Sildenafil in Resistant Hypertensives and Genetic Polymorphism
NCT01392638 ·Status: COMPLETED ·Phase: NA
-
Effects of Sildenafil on Penile Vascular Function in Hypertensive Men With Erectile Dysfunction
NCT02620995 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Sodium Nitrate on Blood Flow in Becker Muscular Dystrophy
NCT02147639 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Versus To Viagra® Oral Tablet.
NCT01254383 ·Status: COMPLETED ·Phase: PHASE1
-
Sildenafil in Single Ventricle Patients
NCT01169519 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Compare the Blood Levels of Sildenafil Following Administration of an Experimental Tablet vs. the Conventional Oral Tablet in Healthy Subjects
NCT00866463 ·Status: COMPLETED ·Phase: PHASE1
-
Using Thermography to Assess the Affects of Sildenafil Cream, 3.6%
NCT05765487 ·Status: COMPLETED ·Phase: PHASE1
-
Sildenafil to Repair Brain Injury Secondary to Birth Asphyxia
NCT04169191 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study to Evaluate a Possible Superiority Expressed by the Faster Onset of Action and the Efficacy and Safety of Sildenafil Citrate 20mg Sublingual Tablet in the Treatment of Erectile Dysfunction of Different Etiologies
NCT01321489 ·Status: UNKNOWN ·Phase: PHASE3
-
Role of Skeletal Muscle Nitric Oxide Production in Age-related Fatigue and Fatigability
NCT01059994 ·Status: COMPLETED ·Phase: NA
-
New Treatment in Erectile Dysfunction Patients.
NCT05439486 ·Status: UNKNOWN ·Phase: NA
-
Effect of Tadalafil on Exercise Capacity in Pediatric Fontan Patients
NCT01291069 ·Status: COMPLETED ·Phase: PHASE1
-
A Randomized Controlled Trial Evaluating Sildenafil Citrate in Relieving Ureteral Stent Related Symptoms
NCT02345980 ·Status: COMPLETED ·Phase: PHASE4
-
Reduced Cardiovascular Morbi-mortality by Sildenafil in Patients With Arterial Claudication
NCT02387450 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
"As Required" Oral Sildenafil in Raynaud's Phenomenon
NCT02050360 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
The Impact of Sildenafil on the Pulmonary Circulation in Healthy Trained and Untrained Humans
NCT04985929 ·Status: COMPLETED ·Phase: PHASE2
-
A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children With Pulmonary Arterial Hypertension.
NCT00159913 ·Status: COMPLETED ·Phase: PHASE3
-
Use of Sildenafil for Treatment of Urinary Incontinence
NCT02983461 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Efficacy of Phosphodiesterase-type 5 Inhibitors in Patients With Univentricular Congenital Heart Disease
NCT03997097 ·Status: WITHDRAWN ·Phase: PHASE3
-
Sodium Nitrate to Improve Blood Flow
NCT02847975 ·Status: COMPLETED ·Phase: PHASE1