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Magnetic Resonance Angiography for Peripheral Arterial Disease (PAD)

NCT00707876 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 119

Last updated 2026-04-16

Study results available
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Summary

The purpose of this study is to compare the difference between two magnetic resonance imaging (MRI) techniques for visualizing arteries. The study hypothesizes that one method that relies upon imaging flowing blood in the pelvic and leg arteries will not be as accurate or efficient as injecting a safe imaging agent to change the appearance of the blood on the MRI. Both methods will be compared with Digital Subtraction Angiography (DSA).

Conditions

  • Peripheral Arterial Disease (PAD)

Interventions

DRUG

ferumoxytol

1.0 mg/kg IV ferumoxytol

DRUG

ferumoxytol

2.5 mg/kg IV ferumoxytol

DRUG

ferumoxytol

4.0 mg/kg IV ferumoxytol

Sponsors & Collaborators

  • AMAG Pharmaceuticals, Inc.

    lead INDUSTRY

Principal Investigators

  • William Strauss, MD · AMAG Pharmaceuticals, Inc.

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-09-01
Primary Completion
2010-07-02
Completion
2020-08-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00707876 on ClinicalTrials.gov