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Mechanisms of Exercise-induced Bronchospasm

NCT00701025 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2021-11-01

No results posted yet for this study

Summary

The term exercise-induced bronchospasm (EIB) describes acute, transient airway narrowing that occurs during, and most often after, exercise. Manifestations of EIB can range from mild impairment of performance to severe bronchospasm and respiratory failure.

The pathogenesis of EIB remains controversial and the role of airway inflammation has not yet been definitively characterized. We plan on comparing markers of inflammation in asthmatic participants with and without EIB at baseline and after bronchoprovocation with eucapnic voluntary hyperventilation testing (EVH). We also will collect demographic information as well as information about asthma control and exercise habits.

Conditions

  • Exercise-induced Bronchospasm

Sponsors & Collaborators

  • Ohio State University

    lead OTHER

Principal Investigators

  • Jonathan P. Parsons, M.D. · Ohio State University

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-04-30
Primary Completion
2011-02-28
Completion
2011-02-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00701025 on ClinicalTrials.gov