Trial Outcomes & Findings for A Comparison of Two Contact Lenses (NCT NCT00700752)

NCT ID: NCT00700752

Last Updated: 2015-05-21

Results Overview

Subjective rating of overall comfort using a 0 through 5 scale. 0=n/a, 1=poor, 2=fair, 3=good, 4=very good, 5=excellent. Scores from 2-week and 4-week visits were combined for final values.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

40 participants

Primary outcome timeframe

after 4 weeks of lens wear

Results posted on

2015-05-21

Participant Flow

Participant milestones

Participant milestones
Measure
Senofilcon A/Balafilcon A
senofilcon A silicone hydrogel contact lens worn first, balafilcon A silicone hydrogel contact lens worn second.
Balafilcon A/Senofilcon A
balafilcon A silicone hydrogel contact lens worn first, senofilcon A silicone hydrogel contact lens worn second.
First Intervention
STARTED
20
20
First Intervention
COMPLETED
20
18
First Intervention
NOT COMPLETED
0
2
Second Intervention
STARTED
20
18
Second Intervention
COMPLETED
20
18
Second Intervention
NOT COMPLETED
0
0

Reasons for withdrawal

Reasons for withdrawal
Measure
Senofilcon A/Balafilcon A
senofilcon A silicone hydrogel contact lens worn first, balafilcon A silicone hydrogel contact lens worn second.
Balafilcon A/Senofilcon A
balafilcon A silicone hydrogel contact lens worn first, senofilcon A silicone hydrogel contact lens worn second.
First Intervention
Withdrawal by Subject
0
2

Baseline Characteristics

A Comparison of Two Contact Lenses

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Overall
n=38 Participants
Completed study population
Age, Continuous
24.4 years
STANDARD_DEVIATION 3.4 • n=39 Participants
Sex: Female, Male
Female
29 Participants
n=39 Participants
Sex: Female, Male
Male
9 Participants
n=39 Participants
Region of Enrollment
United States
38 participants
n=39 Participants

PRIMARY outcome

Timeframe: after 4 weeks of lens wear

Subjective rating of overall comfort using a 0 through 5 scale. 0=n/a, 1=poor, 2=fair, 3=good, 4=very good, 5=excellent. Scores from 2-week and 4-week visits were combined for final values.

Outcome measures

Outcome measures
Measure
Senofilcon A
n=38 Participants
silicone hydrogel contact lens worn daily with a 2-week replacement regimen.
Balafilcon A
n=38 Participants
silicone hydrogel contact lens worn daily with a 4-week replacement regimen
Patient-reported Comfort at at the Manufacturer's Recommended Lens Replacement Timeframe of 2-weeks (Senofilcon A) or 4-weeks (Balafilcon A).
4.0074 Units on a scale
Standard Error 0.2008
2.8438 Units on a scale
Standard Error 0.1972

Adverse Events

Senofilcon A/Balafilcon A

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Balafilcon A/Senofilcon A

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kurt Moody OD

Vistakon

Phone: 904-443-3088

Results disclosure agreements

  • Principal investigator is a sponsor employee The PI may not publish, divulge, reveal, disclose, or use the data and or results of the study without prior written consent of Vistakon.
  • Publication restrictions are in place

Restriction type: OTHER