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Dose Response to Topical Glyceryl Trinitrate in Patients With Raynaud's Phenomenon

NCT00700518 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2008-12-30

No results posted yet for this study

Summary

The purpose of this study is to evaluate the blood flow response to topical Glyceryl Trinitrate when applied to the skin of patient's fingers with Raynaud's Phenomenon.

Conditions

  • Raynaud's Phenomenon

Interventions

DRUG

placebo cream

placebo cream applied to 2 adjacent fingers of non-dominant hand one time

DRUG

Glyceryl Trinitrate

0.6mg of Glyceryl Trinitrate applied to 2 adjacent fingers on non-dominant hand one time

DRUG

Glyceryl Trinitrate

1.2mg Glyceryl Trinitrate topically to 2 adjacent fingers of non-dominant hand one time

DRUG

Glyceryl Trinitrate

1.8mg Glyceryl Trinitrate topically to 2 adjacent fingers of non-dominant hand one time

DRUG

Glyceryl Trinitrate

2.4 mg Glyceryl Trinitrate topically to 2 adjacent fingers of non-dominant hand one time

Sponsors & Collaborators

  • Procris Pharmaceuticals

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-06-30
Primary Completion
2008-11-30
Completion
2008-11-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00700518 on ClinicalTrials.gov