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ABCB4 Gene Mutations in Intrahepatic Cholestasis of Pregnancy and Controls

NCT00700232 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2010-06-17

No results posted yet for this study

Summary

Mutations of the ATP binding cassette subfamily B member 4 (ABCB4) gene, a gene involved in a subtype of progressive familial intrahepatic cholestasis, have been reported in women suffering from intrahepatic cholestasis of pregnancy. The true incidence and the role of these ABCB4 gene mutations in patients suffering from intrahepatic cholestasis of pregnancy have not been clearly established.

The aim of the present study is to describe the nature and frequency of these mutations in a series of patients with intrahepatic cholestasis of pregnancy and to compare with a control group of pregnant women without intrahepatic cholestasis of pregnancy.

Conditions

  • Intrahepatic Cholestasis of Pregnancy

Sponsors & Collaborators

  • University Hospital, Tours

    lead OTHER

Principal Investigators

  • BACQ Yannick, MD · Service d'hépato-gastro-entérologie CHRU Tours

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-07-31
Primary Completion
2008-07-31
Completion
2009-07-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00700232 on ClinicalTrials.gov