Long Term Follow up Study of Predictive Markers in GHD and TS Children
NCT00699855 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 182
Last updated 2014-02-19
Summary
Primary objective is to assess the relationship between changes from serum biomarkers observed after 1 month of Saizen® therapy and change in height, weight after up to 5 years of treatment with Growth Hormone in children with Growth Hormone Deficiency (GHD) and Turner Syndrome (TS).
Conditions
- Growth Hormon Deficiency
- Turner Syndrome in Pre-pubertal Children
Sponsors & Collaborators
-
Merck KGaA, Darmstadt, Germany
lead INDUSTRY
Principal Investigators
-
Gilles Della Corte · Merck Serono S.A., Geneva
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-09-30
- Primary Completion
- 2012-08-31
- Completion
- 2012-08-31
More Related Trials
-
An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD)
NCT01806298 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate Subjects With Turner Syndrome Treated With Growth Hormone
NCT00097552 ·Status: COMPLETED
-
Metabolic Endocrinology and Growth Hormone in Adults
NCT01080755 ·Status: COMPLETED
-
Long-Term Growth and Skeletal Effects of Early Growth Hormone Treatment in Turner Syndrome
NCT00266656 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety Evaluation of Recombinant Human Growth Hormone (r-hGH), Saizen®, on a Population of Children With Hypochondroplasia, Treated at Least 3 Years or Until Near Final Height, When Applicable, in Comparison With a Historic Cohort of Non-treated Children
NCT01111019 ·Status: COMPLETED ·Phase: PHASE2
-
First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study
NCT01419249 ·Status: COMPLETED ·Phase: PHASE4
-
Saizen in Intra-uterine Growth Retardation
NCT01400698 ·Status: COMPLETED ·Phase: PHASE3
-
Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone Deficiency
NCT00109733 ·Status: COMPLETED ·Phase: PHASE3
-
Influence of Adherence to Growth Hormone Therapy (GHT) With Norditropin® on Near Final Height in Patients With Growth Hormone Deficiency (GHD) and Born Small for Gestational Age (SGA)
NCT03972345 ·Status: ENROLLING_BY_INVITATION
-
A Pharmaco-epidemiological Study of Short Patients Born Small for Gestational Age (SGA), Treated With Saizen® (Recombinant Somatropin)
NCT01082354 ·Status: COMPLETED
-
Saizen® Solution for Injection Adult Growth Hormone Deficiency (GHD) Immunogenicity Study
NCT01237340 ·Status: TERMINATED ·Phase: PHASE3
-
Long-term Safety and Effectiveness of Growth Hormone With GHD, TS, CRF, SGA , ISS and PWS in Children
NCT01604395 ·Status: RECRUITING
-
Growth Response in Girls With Turner Syndrome
NCT01734486 ·Status: COMPLETED ·Phase: PHASE4
-
Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders
NCT07221851 ·Status: RECRUITING ·Phase: PHASE3
-
Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation
NCT01073605 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial to Evaluate the Correlation Between Spontaneous Catch-up Growth, Clinical Response to Saizen (Recombinant Human Growth Hormone, r-hGH) and Gene Expression Profiling in Children Small for Gestational Age (SGA)
NCT01067352 ·Status: TERMINATED ·Phase: PHASE3
-
Transition Study: Growth Hormone Therapy In Partial Growth Hormone Deficient Adolescents
NCT00156143 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of PEG-somatropin Injection to Treat Children of Turner Syndrome
NCT03189160 ·Status: UNKNOWN ·Phase: PHASE2
-
Prepubertal Children With Growth Failure Associated With Primary Insulin-Like Growth Factor-1 (IGF-1) Deficiency
NCT00125164 ·Status: COMPLETED ·Phase: PHASE3
-
Study Aimed At Improving Height With Genotonorm In Children Born Little And/Or Light With Growth Retardation At The Age
NCT00174252 ·Status: COMPLETED ·Phase: PHASE3
-
Retrospective Study Of The Influence Of Age At Start Of Growth Hormone Treatment On Height Gain In Children Born Small for Gestational Age
NCT01897753 ·Status: COMPLETED
-
Prevention of Growth Retardation by Early Treatment With Growth Hormone (GH) in Children With CJA Treated by Corticosteroid Therapy
NCT00174291 ·Status: TERMINATED ·Phase: PHASE3
-
A Clinical Study to Assess the Efficacy and Safety of DA-3002
NCT01813630 ·Status: COMPLETED ·Phase: PHASE3
-
IGF1 Generation Test
NCT00145457 ·Status: COMPLETED ·Phase: PHASE4
-
Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children (Clinical Trial I)
NCT02380235 ·Status: UNKNOWN ·Phase: PHASE4