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A Controlled Trial of Mifepristone in Gulf War Veterans With Chronic Multisymptom Illness

NCT00691067 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 65

Last updated 2017-01-31

No results posted yet for this study

Summary

We propose to conduct placebo-controlled trial of the glucocorticoid receptor antagonist mifepristone in Gulf War veterans (GWV) with chronic multisymptom illness (CMI) to examine its effects on physical and mental health and cognitive functioning. In addition, we propose to examine whether HPA axis biomarkers or their response to mifepristone are useful predictors of clinical response.

Conditions

  • Chronic Multisymptom Illness in Gulf War Veterans

Interventions

DRUG

mifepristone

200 mg po per day x 6 weeks

DRUG

Placebos

placebo

Sponsors & Collaborators

  • U.S. Army Medical Research and Development Command

    collaborator FED

  • Bronx Veterans Medical Research Foundation, Inc

    lead OTHER

Principal Investigators

  • Julia A Golier, M.D. · James J Peters VA Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
35 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-05-31
Primary Completion
2012-08-31
Completion
2012-08-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00691067 on ClinicalTrials.gov