Platelet Reactivity After Cessation of Clopid in the Setting of Coronary Stent Implantation I: PRACTICE I
NCT00684359 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2010-05-31
Summary
Single center randomized parallel group study to determine if:
1. there is a temporary increase in platelet reactivity after abrupt discontinuation of clopidogrel due to a potential rebound phenomenon.
2. the effect of sudden discontinuation of clopidogrel 6 months post coronary angioplasty with adjunct drug eluting stent implantation compared to 12 month continuation of clopidogrel on platelet reactivity. And the association with MACE up to 12 months post coronary angioplasty.
Conditions
- Coronary Disease
Sponsors & Collaborators
-
Medstar Health Research Institute
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-06-30
- Completion
- 2010-02-28
Countries
- United States
Study Locations
More Related Trials
-
Pharmacodynamic Study on Efficacy of Clopidogrel With St. John's Wort
NCT01330589 ·Status: WITHDRAWN ·Phase: NA
-
Resistance to Antithrombotic Therapy
NCT00858715 ·Status: COMPLETED ·Phase: NA
-
Tailoring Of Platelet Inhibition to Avoid Stent Thrombosis
NCT00914368 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of Intensive Antiplatelet Therapy for Patients With Clopidogrel Resistance After Coronary Stent Implantation
NCT01094457 ·Status: COMPLETED ·Phase: PHASE4
-
Continuous Clopidogrel Dose Adjustment in Acute Coronary Syndrome Patients With High On-treatment Platelet Reactivity
NCT02096419 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Clopidogrel on Coated-Platelets in Patients Undergoing Cardiac Catheterization
NCT00644657 ·Status: COMPLETED ·Phase: NA
-
Safety and Efficacy of Six Months Dual Antiplatelet Therapy After Drug-Eluting Stenting
NCT00661206 ·Status: UNKNOWN ·Phase: PHASE4
-
The Comparison of Effects Between Increased Dose of Clopidogrel and Addition of Cilostazol
NCT00620646 ·Status: COMPLETED ·Phase: NA
-
Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel (TRIGGER-PCI)
NCT00910299 ·Status: TERMINATED ·Phase: PHASE2
-
Evaluating Additional Platelet Inhibition in Patients With High Platelet Reactivity Undergoing Percutaneous Coronary Intervention
NCT01339026 ·Status: TERMINATED ·Phase: PHASE4
-
Effect of Clopidogrel Loading and Risk of PCI
NCT00457236 ·Status: UNKNOWN
-
Adjunctive Cilostazol Versus High Maintenance-dose Clopidogrel According to Cytochrome 2C19 Polymorphism
NCT01012193 ·Status: COMPLETED ·Phase: PHASE4
-
Impact of Clopidogrel Dose Adjustment According to Platelet Reactivity Monitoring in Patients With High on Treatment Platelet Reactivity Undergoing Percutaneous Coronary Intervention
NCT01505790 ·Status: COMPLETED ·Phase: PHASE3
-
Association of Clopidogrel Therapy and Stent Thrombosis
NCT00484926 ·Status: COMPLETED ·Phase: PHASE4
-
Clopidogrel Reloading in Clopidogrel Resistant Patients With ACS
NCT00444132 ·Status: COMPLETED ·Phase: PHASE3
-
Clopidogrel Resistance and the Possibility of Its Affection
NCT00839345 ·Status: TEMPORARILY_NOT_AVAILABLE
-
Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery
NCT01146301 ·Status: COMPLETED ·Phase: PHASE4
-
Platelet Function Monitoring in Patients Treated With Clopidogrel at the Time of Primary Percutaneous Coronary Angioplasty
NCT00827346 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Platelet Function Assessment for Atherothrombotic Patients
NCT00513149 ·Status: UNKNOWN ·Phase: PHASE4
-
Antiplatelet Resistance Research in Patients With Peripheral Arterial Revascularization
NCT03953547 ·Status: COMPLETED
-
Clopidogrel Maintaining Dosage in Acute Coronary Syndrome After Drug Eluting Stent Implantation
NCT00404053 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Different Dosing Regimens of Clopidogrel Before Elective Percutaneous Coronary Intervention (PCI) on Platelet Function
NCT00693069 ·Status: COMPLETED ·Phase: PHASE3
-
Role of Plavix in Hemorrhagic and Ischemic Complications of Catheterization.
NCT00421252 ·Status: TERMINATED ·Phase: PHASE4
-
Effect of Prasugrel Versus Clopidogrel on Platelet Function After Bivalirudin Cessation
NCT01789814 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Atorvastatin Versus Pravastatin on Platelet Inhibition by Clopidogrel
NCT00405717 ·Status: COMPLETED ·Phase: PHASE4